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Update of the drug resistance mutations in HIV-1: December 2010.

Author: Brun-VézinetFrançoise, ClotetBonaventura, GünthardHuldrych F, JohnsonVictoria A, KuritzkesDaniel R, PillayDeenan, RichmanDouglas D, SchapiroJonathan M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This update to the International AIDS Society-USA (IAS-USA) drug resistance mutations list includes 9 new mutations, changes to tipranavir/ritonavir mutations, and updates to user notes.
Paper Details　
Original Abstract of the Article :
This December 2010 version of the International AIDS Society-USA (IAS-USA) drug resistance mutations list updates the figures last published in December 2009 (Johnson VA et al, Top HIV Med, 2009;17:138-145). This update includes 9 new mutations- E138G and E138K for etravirine (Haddad M et al, CROI, ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/21245516

データ提供：米国国立医学図書館（NLM）

HIV-1 Drug Resistance: An Ever-Evolving Landscape

The fight against HIV-1 is an ongoing battle, with the virus constantly evolving and developing resistance to antiviral medications. This update of the International AIDS Society-USA (IAS-USA) drug resistance mutations list provides a valuable resource for clinicians and researchers working in the field. The update includes nine new mutations associated with resistance to various antiretroviral drugs, including etravirine, raltegravir, and tipranavir/ritonavir. This information is essential for understanding the mechanisms of drug resistance and for developing effective treatment strategies.

A Constant Struggle Against Resistance

The emergence of new drug resistance mutations highlights the importance of ongoing research and surveillance in the fight against HIV-1. Clinicians must stay informed about the latest mutations to effectively monitor patients and adjust treatment regimens as needed.

A Multi-Faceted Approach to HIV-1 Treatment

This update underscores the need for a multi-faceted approach to HIV-1 treatment, encompassing not only the selection of appropriate medications but also comprehensive patient monitoring and ongoing research to stay ahead of the virus's evolving resistance mechanisms.

Dr.Camel's Conclusion

The fight against HIV-1 is like a desert expedition, requiring constant vigilance and adaptation to navigate the ever-changing landscape of drug resistance. This update of the drug resistance mutations list serves as a vital compass, guiding clinicians and researchers in their efforts to combat this challenging virus.

Date :
  1. Date Completed 2011-02-16
  2. Date Revised 2011-06-08
Further Info :

Pubmed ID

21245516

DOI: Digital Object Identifier

21245516

Related Literature

Article Analysis
・Effects of tipranavir
SNS
PICO Info
in preparation
Languages

English

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