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Lanthanum carbonate versus sevelamer hydrochloride: improvement of metabolic acidosis and hyperkalemia in hemodialysis patients.
Author: FiliopoulosVassilis, HadjiyannakosDimitrios, KoutisIoannis, LazarouDimitrios, TrompoukiSofia, VlassopoulosDimosthenis
Original Abstract of the Article :
Sevelamer hydrochloride (SH) has been reported to aggravate metabolic acidosis and hyperkalemia. This study was performed to evaluate acid-base status and serum potassium changes after replacing SH with lanthanum carbonate (LC) in hemodialysis patients. SH was prescribed for 24 weeks in 14 stable he...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/j.1744-9987.2010.00868.x
データ提供:米国国立医学図書館(NLM)
Lanthanum Carbonate vs. Sevelamer Hydrochloride: A Showdown in the Desert of Hemodialysis
Today, we venture deep into the desert of hemodialysis, a landscape where maintaining mineral balance is a constant struggle. This study, like a team of intrepid explorers, compared the effects of two phosphate binders, lanthanum carbonate (LC) and sevelamer hydrochloride (SH), on metabolic acidosis and hyperkalemia in patients undergoing hemodialysis.
Lanthanum Carbonate: A Potential Oasis for Acid-Base Balance
The researchers found that switching from SH to LC led to significant improvements in metabolic acidosis and hyperkalemia. Imagine a parched traveler discovering a hidden oasis, where the air is cool and fresh, and the water is sweet and plentiful. Lanthanum carbonate, in this analogy, represents the oasis, offering relief from the metabolic imbalances that often plague patients undergoing hemodialysis.
Navigating the Desert of Hemodialysis with Caution
However, while LC offered potential benefits, the study also revealed a potential drawback - gastrointestinal side effects. Just as a desert traveler must be wary of mirages, we must approach LC with caution, mindful of its potential for gastrointestinal upset. Further research is needed to optimize the use of LC, balancing its benefits with potential side effects.
Dr.Camel's Conclusion
This research, like a guidebook through the desert of hemodialysis, offers valuable insights into the potential advantages and challenges of different phosphate binders. While lanthanum carbonate may provide a refreshing oasis for acid-base balance, its potential side effects must be carefully considered. As we continue to explore the desert of hemodialysis, finding the right balance between treatments and minimizing side effects remains paramount.
Date :
- Date Completed 2011-07-07
- Date Revised 2022-04-08
Further Info :
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