Corticosteroid therapy in the treatment of pediatric patients with atopic dermatitis.

Author: ArtsDanielle, FröschlBarbara, LeopoldChristine

Paper Details 
Original Abstract of the Article :
HEALTH POLITICAL BACKGROUND: In developed countries 2.5% of the population - mainly children - are affected by atopic dermatitis. During the past few years its prevalence amongst school children has risen decisively and now lies between 8% to 16%. It is the most frequent chronic skin disease amongst...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011329/

データ提供:米国国立医学図書館(NLM)

Navigating the Complexities of Atopic Dermatitis in Children

Atopic dermatitis, a common skin condition, can significantly impact the quality of life of children. This study explores the effectiveness and efficiency of various topical anti-inflammatory treatments for atopic dermatitis, including corticosteroids and calcineurin inhibitors. The researchers conducted a systematic review of 24 publications and found that tacrolimus, a calcineurin inhibitor, was more effective than hydrocortisone acetate for moderate to severe atopic dermatitis. They also found that intermittent treatment with pimecrolimus, another calcineurin inhibitor, could reduce the need for topical corticosteroids. These findings suggest that calcineurin inhibitors may be a valuable alternative to corticosteroids in the treatment of atopic dermatitis.

Calcineurin Inhibitors: A Potential Solution for Atopic Dermatitis

This study provides compelling evidence for the efficacy of calcineurin inhibitors in treating atopic dermatitis in children. The findings suggest that these agents may be more effective than corticosteroids, particularly for moderate to severe cases. Furthermore, the potential for intermittent treatment with pimecrolimus to reduce corticosteroid use is encouraging, as it could minimize potential side effects associated with long-term corticosteroid therapy. This research offers valuable insights for clinicians seeking optimal treatment strategies for atopic dermatitis in children.

The Skin: A Desert Oasis of Protection

Imagine the skin as a vast desert, where the outer layers act as a protective barrier against environmental aggressors. Atopic dermatitis, like a sandstorm, can disrupt this protective barrier, leading to inflammation and discomfort. Topical treatments, like oases in the desert, can provide relief and nourishment to the affected skin. This study's findings suggest that calcineurin inhibitors may be a particularly effective oasis, offering a more potent and potentially safer treatment option for atopic dermatitis.

Dr.Camel's Conclusion

This study explores the complex landscape of atopic dermatitis treatment in children. The research suggests that calcineurin inhibitors may offer a more effective and potentially safer alternative to corticosteroids for this condition. The findings highlight the importance of personalized treatment approaches, taking into account the severity of the condition and the individual patient's needs. Further research is needed to fully understand the long-term safety and efficacy of calcineurin inhibitors in the treatment of atopic dermatitis.

Date :
  1. Date Completed 2011-07-14
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

21289943

DOI: Digital Object Identifier

PMC3011329

Related Literature

SNS
PICO Info
in preparation
Languages

English

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