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Effect of drugs on high-density lipoprotein.

Author: McKenneyJames M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

The clinical management of dyslipidemic patients is discussed, including the use of fibrates and niacin for raising high-density lipoprotein cholesterol (HDL-C) levels. Statins are most useful for their LDL-C-lowering efficacy, and niacin is the most effective drug for augmenting HDL-C-raising.
Paper Details　
Original Abstract of the Article :
The National Cholesterol Education Program Adult Treatment Panel III found evidence for raising high-density lipoprotein cholesterol (HDL-C) to reduce coronary artery disease (CAD) events supports use of HDL-C to help modify low-density lipoprotein cholesterol (LDL-C)-lowering goals, but not to esta...See full text at original site
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引用元：
https://doi.org/10.1016/j.jacl.2007.01.004

データ提供：米国国立医学図書館（NLM）

HDL Cholesterol: Unveiling the Secrets of Heart Health

The field of [cardiology and lipid metabolism] is a complex one, filled with intricate mechanisms governing cholesterol levels and their impact on cardiovascular health. This research delves into the role of high-density lipoprotein cholesterol (HDL-C), often referred to as 'good cholesterol,' in reducing the risk of coronary artery disease (CAD). The study explores the effects of various medications on HDL-C levels and their implications for managing dyslipidemia, a condition characterized by abnormal cholesterol levels.

The Power of Medications in Modulating Cholesterol

The study highlights the effectiveness of statins, fibrates, and niacin in modulating cholesterol levels, particularly in patients with atherogenic dyslipidemia, a type of dyslipidemia associated with an increased risk of CAD. These medications, like skilled desert explorers navigating a complex landscape, work to raise HDL-C levels and lower LDL-C (low-density lipoprotein cholesterol, or 'bad cholesterol'), potentially reducing the risk of heart disease. However, the study also emphasizes the importance of considering potential interactions and side effects when using these medications.

A Holistic Approach to Heart Health

This research underscores the importance of a holistic approach to heart health, taking into account both dietary and lifestyle factors in addition to medication. It's a reminder that maintaining a balanced diet, engaging in regular physical activity, and managing stress are crucial for preventing heart disease. Think of it as a comprehensive approach to navigating the desert of heart health, where a healthy lifestyle is essential for reaching the oasis of well-being.

Dr.Camel's Conclusion

This research offers valuable insights into the role of HDL-C in heart health and the effectiveness of various medications in managing dyslipidemia. It's a reminder that maintaining healthy cholesterol levels requires a comprehensive approach, encompassing both medication and lifestyle modifications.

Date :
  1. Date Completed 2012-10-02
  2. Date Revised 2011-02-04
Further Info :

Pubmed ID

21291670

DOI: Digital Object Identifier

10.1016/j.jacl.2007.01.004

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English

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