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Treatment of palmoplantar psoriasis with infliximab: a randomized, double-blind placebo-controlled study.

Author: BissonnetteR, BolducC, GuentherL, LyndeC W, NigenS, PoulinY

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Infliximab was more effective than placebo in improving palmoplantar psoriasis area and severity index (m-PPPASI) in patients with non-pustular palmoplantar psoriasis, suggesting potential for treatment but requiring further investigation.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Palmoplantar psoriasis is a difficult to treat variant of plaque psoriasis. OBJECTIVE: To study the safety and efficacy of infliximab in non-pustular palmoplantar psoriasis. METHODS: Patients with non-pustular palmoplantar psoriasis affecting at least 10% of their palms and soles and w...See full text at original site
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引用元：
https://doi.org/10.1111/j.1468-3083.2011.03984.x

データ提供：米国国立医学図書館（NLM）

Palmoplantar Psoriasis: Seeking Effective Treatment Options

Palmoplantar psoriasis, a challenging skin condition, can be likened to a thorny desert plant, difficult to tame. This study investigates the potential of infliximab, a biologic medication, in treating this stubborn form of psoriasis.

Infliximab Shows Promise in Treating Palmoplantar Psoriasis

The study, while a pilot, suggests that infliximab may be more effective than placebo in reducing palmoplantar psoriasis severity. This is like finding a hidden oasis in the desert, offering potential relief from a persistent condition. However, the authors acknowledge the need for larger and longer-term studies to fully evaluate the efficacy of this treatment.

Navigating the Desert of Psoriasis Treatment

This study provides a beacon of hope for patients struggling with palmoplantar psoriasis. It highlights the potential benefits of infliximab, a promising addition to the treatment landscape. The authors emphasize the importance of ongoing research to refine and expand treatment options for this challenging condition.

Dr.Camel's Conclusion

This study offers a glimmer of hope for patients seeking effective treatment for palmoplantar psoriasis, providing evidence that infliximab may offer a potential path to relief. The research underscores the importance of continued exploration and innovation in this field, with the goal of finding lasting solutions for those who navigate the desert of psoriasis.

Date :
  1. Date Completed 2012-03-06
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

21349113

DOI: Digital Object Identifier

10.1111/j.1468-3083.2011.03984.x

Related Literature

Article Analysis
・Effective treatment of psoriasis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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