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Pharmacochemistry of the platelet purinergic receptors.

Author: CostanziStefano, DeflorianFrancesca, JacobsonKenneth A, MishraShilpi

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Platelets contain purinergic G protein-coupled receptors that are involved in platelet function. New pharmacological tools are being developed to control platelet function.
Paper Details　
Original Abstract of the Article :
Platelets contain at least five purinergic G protein-coupled receptors, e.g., the pro-aggregatory P2Y(1) and P2Y(12) receptors, a P2Y(14) receptor (GPR105) of unknown function, and anti-aggregatory A(2A) and A(2B) adenosine receptor (ARs), in addition to the ligand-gated P2X1 ion channel. Probing th...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166987/

データ提供：米国国立医学図書館（NLM）

Platelet Purinergic Receptors: A Deep Dive into the Desert of Platelet Function

Platelets, tiny blood cells responsible for blood clotting, play a crucial role in maintaining our health. This research explores the complex world of platelet purinergic receptors, which are involved in regulating platelet function. It's like exploring a vast desert of cellular mechanisms, seeking to understand the intricate workings of these tiny blood cells.

Purinergic Receptors: A Key to Understanding Platelet Function

The review delves into the fascinating world of platelet purinergic receptors, highlighting their role in regulating platelet aggregation and other functions. It's like a desert explorer mapping the intricate network of pathways that control platelet activity. The review underscores the potential of targeting these receptors for developing new treatments for cardiovascular diseases.

Implications for Cardiovascular Health

This research sheds light on the intricate mechanisms that govern platelet function, providing a deeper understanding of cardiovascular disease. It's like discovering a hidden oasis in the desert of cardiovascular research, revealing new avenues for treating and preventing cardiovascular disease. The review emphasizes the importance of developing selective and safe drugs that target specific purinergic receptors to optimize treatment outcomes.

Dr.Camel's Conclusion

This research, like a camel caravan traversing the vast desert of platelet function, offers a comprehensive overview of the intricate world of platelet purinergic receptors. The review highlights the potential of targeting these receptors for developing new treatments for cardiovascular disease, offering a glimmer of hope in the fight against this prevalent health concern.
Date :
  1. Date Completed 2011-11-10
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

21484092

DOI: Digital Object Identifier

PMC3166987

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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