Effects of risedronate and low-dose transdermal testosterone on bone mineral density in women with anorexia nervosa: a randomized, placebo-controlled study.

Author: GleysteenSuzanne, HerzogDavid, KlibanskiAnne, LawsonElizabeth A, MeenaghanErinne, MillerKaren K, MisraMadhusmita, SchoenfeldDavid

Paper Details 
Original Abstract of the Article :
Anorexia nervosa is complicated by severe bone loss and clinical fractures. Mechanisms underlying bone loss in adults with anorexia nervosa include increased bone resorption and decreased formation. Estrogen administration has not been shown to prevent bone loss in this population, and to date, ther...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135194/

データ提供:米国国立医学図書館(NLM)

Investigating Bone Mineral Density in Women with Anorexia Nervosa

This study addresses the significant bone loss and fracture risk associated with anorexia nervosa. The research investigated the potential benefits of risedronate and low-dose transdermal testosterone in improving bone mineral density (BMD) in women with this eating disorder. The study utilized a randomized, placebo-controlled design to compare the effectiveness of these treatments to a control group.

Addressing Bone Loss in Anorexia Nervosa: A Challenging Task

The study's findings highlight the complex nature of bone loss in anorexia nervosa, suggesting that conventional estrogen treatment may not be effective in this population. The research indicates that risedronate and low-dose transdermal testosterone may offer potential therapeutic avenues for addressing bone loss in women with anorexia nervosa. However, further research is needed to confirm these findings and establish optimal treatment strategies.

A Holistic Approach to Anorexia Nervosa: Beyond Bone Health

This study underscores the importance of a holistic approach to managing anorexia nervosa, considering both physical and mental health factors. The research highlights the need for comprehensive treatment plans that address the underlying eating disorder, as well as the associated physical complications.

Dr.Camel's Conclusion

Like a camel navigating a harsh desert environment, individuals with anorexia nervosa face numerous challenges, including bone loss and fracture risk. This study explores potential therapeutic approaches to address this complication, offering a glimmer of hope for improving bone health in this vulnerable population. The research underscores the need for multifaceted treatment strategies that encompass both physical and mental well-being.

Date :
  1. Date Completed 2011-09-12
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

21525157

DOI: Digital Object Identifier

PMC3135194

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.