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Cost and cost-effectiveness of switching from d4T or AZT to a TDF-based first-line regimen in a resource-limited setting in rural Lesotho.
Author: BygraveHelen, ClearySusan, FordNathan, GadotLaurent, GoemaereEric, HilderbrandKatherine, JouquetGuillaume, KranzerKatharina, LeeJanice, MakakoleLipontso, TrivinoLaura, VlahakisNatalie
Original Abstract of the Article :
BACKGROUND: Latest World Health Organization guidelines recommend shifting away from Stavudine (d4T)-based regimens due to severe side effects. However, widespread replacement of d4T by Tenofovir (TDF) or Zidovudine (AZT) is hampered by cost concerns. METHODS: We established the cost-effectiveness ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1097/QAI.0b013e31822a9f8d
データ提供:米国国立医学図書館(NLM)
Cost-Effectiveness of Switching to TDF-Based Antiretroviral Regimens in Lesotho
The fight against HIV/AIDS is a global priority, and the development of effective antiretroviral therapies has been a cornerstone of this battle. This research examines the cost-effectiveness of switching from Stavudine (d4T)-based regimens to Tenofovir (TDF)-based regimens in a resource-limited setting in rural Lesotho. The authors employed a comprehensive analysis of cost, utilization, and patient outcomes to determine the optimal approach to first-line antiretroviral therapy.
Prioritizing Cost-Effectiveness in HIV Treatment
The study demonstrates that while TDF-based regimens are more costly than d4T, they are also more effective, leading to fewer side effects and improved quality of life for patients. The findings underscore the importance of considering both cost and effectiveness when making treatment decisions, particularly in resource-limited settings.
Improving HIV Treatment Outcomes
This research highlights the need for greater access to TDF-based antiretroviral therapy in resource-limited settings. By advocating for price reductions and increased generic manufacturing of TDF and its partner drugs, we can improve treatment outcomes for individuals living with HIV/AIDS and make a significant contribution to the global fight against this devastating disease.
Dr. Camel's Conclusion
This study underscores the importance of finding cost-effective solutions for HIV treatment, especially in resource-limited settings. It's a reminder that we must work together to ensure that everyone, regardless of their location, has access to quality healthcare and the best possible treatment options. By prioritizing cost-effectiveness and promoting access to essential medications, we can make a real difference in the lives of individuals living with HIV/AIDS.
Date :
- Date Completed 2011-12-07
- Date Revised 2020-09-30
Further Info :
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