Transition from intravenous epoprostenol to oral or subcutaneous therapy in pulmonary arterial hypertension: a retrospective case series and systematic review.

Author: LevyRobert D, OstrowDavid, ParkKirily, SwistonJohn

Paper Details 
Original Abstract of the Article :
Intravenous epoprostenol, a prostaglandin analogue, has been a mainstay of therapy for patients with advanced pulmonary arterial hypertension (PAH) since the early 1990s. This medication has multiple side effects, and sudden discontinuation is potentially associated with severe sequelae. Several rec...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328871/

データ提供:米国国立医学図書館(NLM)

Transitioning from Intravenous Epoprostenol: A Journey Through the Shifting Sands of PAH Treatment

This research examines the complex process of transitioning patients with advanced pulmonary arterial hypertension (PAH) from intravenous epoprostenol, a mainstay therapy, to newer oral or subcutaneous treatments. The study combines a retrospective case series with a systematic review of the literature, offering valuable insights into the challenges and potential benefits of this transition.

Finding New Paths in the Desert of PAH

This study provides a roadmap for navigating the complex terrain of transitioning PAH patients from intravenous epoprostenol to alternative therapies. The findings underscore the importance of careful patient selection, individualized treatment plans, and close monitoring to ensure a smooth and successful transition.

A New Era in PAH Treatment

This research reflects the evolving landscape of PAH treatment, highlighting the emergence of newer oral and subcutaneous therapies that offer potential advantages over traditional intravenous approaches. The study encourages further research to refine these new treatment options and optimize patient outcomes.

Dr. Camel's Conclusion

The desert of PAH treatment is constantly evolving, with new paths emerging in the quest for more effective and convenient therapies. This study highlights the challenges and potential benefits of transitioning patients from intravenous epoprostenol to newer treatment options. By understanding the nuances of this transition, we can ensure the best possible care for patients navigating the complexities of PAH.

Date :
  1. Date Completed 2012-06-11
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

21766080

DOI: Digital Object Identifier

PMC3328871

Related Literature

SNS
PICO Info
in preparation
Languages

English

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