Inactivation of hepatitis A variants during heat treatment (pasteurization) of human serum albumin.

Author: FarcetMaria R, KindermannJohanna, KreilThomas R, ModrofJens

Paper Details 
Original Abstract of the Article :
Pasteurization of human serum albumin (HSA) is detailed in the US and European Pharmacopoeial monographs and therefore a process that allows for little variation in physiochemical variables. Nevertheless, differences of up to 3.9 log in hepatitis A virus (HAV) inactivation by pasteurization have bee...See full text at original site
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引用元:
https://doi.org/10.1111/j.1537-2995.2011.03251.x

データ提供:米国国立医学図書館(NLM)

Hepatitis A Inactivation: The Importance of Variant Selection

In the realm of medicine, ensuring the safety of treatments is of paramount importance. This study investigates the inactivation of hepatitis A virus (HAV) during pasteurization of human serum albumin (HSA), a vital protein used in various medical treatments. The researchers explore the potential impact of HAV variant selection on the effectiveness of pasteurization, aiming to optimize the safety of this critical medical process.

A Delicate Balance: Variant Selection and Virus Inactivation

The study highlights the importance of carefully considering HAV variant selection when assessing the effectiveness of pasteurization for inactivating the virus in human serum albumin. The researchers found that different HAV variants exhibited varying levels of inactivation during the pasteurization process. This discovery emphasizes the need for thorough testing and optimization of pasteurization protocols to ensure the safe and effective use of human serum albumin.

Safeguarding Patient Health: A Priority in Medicine

This study underscores the importance of rigorous testing and quality control measures in ensuring the safety of medical treatments. By carefully considering the impact of factors like HAV variant selection on the efficacy of pasteurization, researchers can contribute to the development of safer and more effective medical products. It's a reminder that the pursuit of patient health requires meticulous attention to detail and a relentless dedication to improving medical practices.

Dr.Camel's Conclusion

Just as a camel carefully navigates the scorching sands of the desert, healthcare professionals carefully navigate the intricate world of medical treatments. This study reveals the importance of selecting appropriate HAV variants for effective pasteurization of human serum albumin, ensuring the safety and efficacy of this critical medical product. It's a testament to the ongoing efforts of researchers to enhance patient safety and improve the quality of healthcare.

Date :
  1. Date Completed 2012-03-13
  2. Date Revised 2013-10-21
Further Info :

Pubmed ID

21790623

DOI: Digital Object Identifier

10.1111/j.1537-2995.2011.03251.x

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SNS
PICO Info
in preparation
Languages

English

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