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Long-term daclizumab therapy for the treatment of noninfectious ocular inflammatory disease.

Author: FaiaLisa, GangaputraSapna, LiZhuging, NussenblattRobert, SenH Nida, SherryPatti, SranPushpa, VitaleSusan, WroblewskiKeith, YehSteven

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Daclizumab was effective in reducing concomitant immunosuppressive medication, stabilizing visual acuity, and preventing uveitic flares in most patients with chronic, noninfectious intermediate and/or posterior uveitis. However, it was associated with dermatologic complications and four patients developed solid tumor malignancies.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: Safety and efficacy of daclizumab during an 11-year period. DESIGN: Structured, retrospective chart review. PARTICIPANTS: Thirty-nine patients. METHODS: Patients with chronic, noninfectious intermediate and/or posterior uveitis. RESULTS: Thirty-nine patients (78 eyes) were treated for...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/21816251

データ提供：米国国立医学図書館（NLM）

Daclizumab: A Long-Term Oasis for Noninfectious Ocular Inflammatory Disease

The eyes are the windows to the soul, and when they are affected by inflammation, it can be a distressing experience. This study examines the long-term safety and efficacy of daclizumab, a medication used to treat chronic, noninfectious inflammation of the middle and back parts of the eye. The researchers reviewed data from 39 patients over an 11-year period, evaluating the drug’s effectiveness in improving vision, reducing the need for other medications, and preventing future inflammation. The study provides a valuable perspective on the long-term use of daclizumab, a beacon of hope for patients battling this challenging condition.

A Long-Term Solution for Eye Inflammation: Daclizumab Shows Promise

The study suggests that daclizumab can be an effective and relatively safe treatment for chronic, noninfectious eye inflammation. Its ability to stabilize vision, reduce the need for other medications, and prevent flares offers a glimmer of hope for patients seeking long-term management of this debilitating condition. This research is an oasis in the desert of ongoing inflammation, offering a pathway to relief and a brighter future.

Navigating the Desert of Eye Inflammation: A Long-Term Solution

This study is a reminder that persistent eye inflammation can be a challenging condition. It highlights the value of daclizumab in providing a long-term solution, helping patients navigate the desert of chronic inflammation and achieve better control over their symptoms.

Dr. Camel's Conclusion

The findings of this study are a valuable oasis in the desert of ocular inflammatory disease. Daclizumab’s potential to provide long-term relief for patients battling this chronic condition is a testament to the power of medical research. By understanding the benefits and risks of this medication, healthcare providers can guide patients toward a path of improved vision and quality of life.

Date :
  1. Date Completed 2011-12-16
  2. Date Revised 2023-06-02
Further Info :

Pubmed ID

21816251

DOI: Digital Object Identifier

NIHMS322318

Related Literature

Article Analysis
・Effects of daclizumab injection
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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