Paper Details

  1. Home
  2. Paper Details

Radiological progression in rheumatoid arthritis: do D-penicillamine and hydroxychloroquine have different effects?

Author: DaviesJ, GreenwoodA, HallN D, MaddisonM C, MaddisonP J, ScottD L

Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Hydroxychloroquine and penicillamine were both effective in treating rheumatoid arthritis. Penicillamine was associated with less initial radiological damage.
Paper Details　
Original Abstract of the Article :
We studied 43 patients with active rheumatoid disease of less than 4 years' duration: 23 were given hydroxychloroquine and 20 penicillamine. Efficacy was assessed using clinical and laboratory variables. Radiological progression was measured using Larsen's method for scoring plain radiographs of the...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1093/rheumatology/29.2.126

データ提供：米国国立医学図書館（NLM）

Rheumatoid Arthritis: Navigating the Treatment Landscape with D-penicillamine and Hydroxychloroquine

This study explores the world of rheumatoid arthritis, a chronic inflammatory disease that affects the joints. Imagine rheumatoid arthritis as a persistent desert wind that relentlessly erodes the joints, causing pain and stiffness. This study delves into the effects of two medications, D-penicillamine and hydroxychloroquine, on the progression of rheumatoid arthritis, seeking to understand their potential benefits and limitations.

D-penicillamine and Hydroxychloroquine: A Tale of Two Treatments

The authors conducted a [research methodology] to compare the efficacy of D-penicillamine and hydroxychloroquine in treating rheumatoid arthritis. Their findings suggest that both medications can effectively manage the disease, but D-penicillamine appears to be associated with less initial radiological damage.

Managing Rheumatoid Arthritis: A Long-Term Perspective

This study underscores the need for long-term management of rheumatoid arthritis, as both D-penicillamine and hydroxychloroquine, while effective, do not prevent the disease's progression. The researchers recommend ongoing monitoring and tailored treatment strategies to minimize joint damage and improve patient quality of life.

Dr. Camel's Conclusion

This research offers valuable insights into the treatment landscape of rheumatoid arthritis. It emphasizes the importance of individualized care and the need for continuous monitoring and adaptation of treatment strategies to address this complex and challenging disease.
Date :
  1. Date Completed 1990-05-17
  2. Date Revised 2019-08-28
Further Info :

Pubmed ID

2182170

DOI: Digital Object Identifier

10.1093/rheumatology/29.2.126

Related Literature

Article Analysis
・Effects of penicillamine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.