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Elevated international normalized ratio values associated with concomitant use of warfarin and ceftriaxone.
Author: BurnsStephanie, ClarkThomas Ross
Original Abstract of the Article :
PURPOSE: The case of a patient receiving long-term warfarin therapy who experienced elevated International Normalized Ratio (INR) values on two occasions after injections of ceftriaxone is reported. SUMMARY: An elderly woman (age, 67 years) with multiple comorbidities who had been receiving warfari...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.2146/ajhp100681
データ提供:米国国立医学図書館(NLM)
Warfarin and Ceftriaxone: A Cautionary Tale
This case report highlights a potential drug interaction between [warfarin] and [ceftriaxone]. Warfarin is a blood thinner commonly used to prevent blood clots, while ceftriaxone is an antibiotic. The report describes a patient who experienced a dangerous increase in their [International Normalized Ratio (INR)] values after receiving injections of ceftriaxone.
Imagine a camel crossing a desert with a delicate balance of water in its hump. Warfarin is like the camel's water supply, carefully regulated to prevent dehydration. Ceftriaxone, in this case, is like a sudden sandstorm that disrupts the camel's balance, potentially leading to dangerous dehydration. The report suggests that ceftriaxone may interfere with the way warfarin is metabolized in the body, causing an increase in INR values and increasing the risk of bleeding.
A Warning for Healthcare Professionals
This case report serves as a cautionary tale for healthcare professionals. It emphasizes the importance of being aware of potential drug interactions, especially when prescribing medications to patients already taking other medications. Close monitoring and careful adjustments to medication dosages may be necessary to avoid dangerous consequences.
The Importance of Patient Safety
This case report underscores the importance of patient safety in healthcare. It highlights the potential dangers of drug interactions and emphasizes the need for careful medication management to prevent adverse events. Healthcare professionals must remain vigilant and stay informed about potential drug interactions to ensure the well-being of their patients.
Dr.Camel's Conclusion
This case report is a reminder that even in the vast desert of medicine, there are hidden dangers that need to be navigated with caution. The interaction between warfarin and ceftriaxone highlights the importance of careful medication management and the need for healthcare professionals to be aware of potential drug interactions to ensure patient safety. It's a reminder that in the realm of medicine, just as in the desert, every step must be taken with a keen eye and a watchful heart.
Date :
- Date Completed 2011-12-12
- Date Revised 2019-01-01
Further Info :
Related Literature
English
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