Elevated international normalized ratio values associated with concomitant use of warfarin and ceftriaxone.

Author: BurnsStephanie, ClarkThomas Ross

Paper Details 
Original Abstract of the Article :
PURPOSE: The case of a patient receiving long-term warfarin therapy who experienced elevated International Normalized Ratio (INR) values on two occasions after injections of ceftriaxone is reported. SUMMARY: An elderly woman (age, 67 years) with multiple comorbidities who had been receiving warfari...See full text at original site
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引用元:
https://doi.org/10.2146/ajhp100681

データ提供:米国国立医学図書館(NLM)

Warfarin and Ceftriaxone: A Cautionary Tale

This case report highlights a potential drug interaction between [warfarin] and [ceftriaxone]. Warfarin is a blood thinner commonly used to prevent blood clots, while ceftriaxone is an antibiotic. The report describes a patient who experienced a dangerous increase in their [International Normalized Ratio (INR)] values after receiving injections of ceftriaxone.

Imagine a camel crossing a desert with a delicate balance of water in its hump. Warfarin is like the camel's water supply, carefully regulated to prevent dehydration. Ceftriaxone, in this case, is like a sudden sandstorm that disrupts the camel's balance, potentially leading to dangerous dehydration. The report suggests that ceftriaxone may interfere with the way warfarin is metabolized in the body, causing an increase in INR values and increasing the risk of bleeding.

A Warning for Healthcare Professionals

This case report serves as a cautionary tale for healthcare professionals. It emphasizes the importance of being aware of potential drug interactions, especially when prescribing medications to patients already taking other medications. Close monitoring and careful adjustments to medication dosages may be necessary to avoid dangerous consequences.

The Importance of Patient Safety

This case report underscores the importance of patient safety in healthcare. It highlights the potential dangers of drug interactions and emphasizes the need for careful medication management to prevent adverse events. Healthcare professionals must remain vigilant and stay informed about potential drug interactions to ensure the well-being of their patients.

Dr.Camel's Conclusion

This case report is a reminder that even in the vast desert of medicine, there are hidden dangers that need to be navigated with caution. The interaction between warfarin and ceftriaxone highlights the importance of careful medication management and the need for healthcare professionals to be aware of potential drug interactions to ensure patient safety. It's a reminder that in the realm of medicine, just as in the desert, every step must be taken with a keen eye and a watchful heart.

Date :
  1. Date Completed 2011-12-12
  2. Date Revised 2019-01-01
Further Info :

Pubmed ID

21856805

DOI: Digital Object Identifier

10.2146/ajhp100681

Related Literature

SNS
PICO Info
in preparation
Languages

English

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