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Potential adverse effects of oseltamivir in rats: males are more vulnerable than females.
Author: Al-KahtaniMohamed Ali, El-SayedWael M
Original Abstract of the Article :
Oseltamivir is the most widely used antiviral drug for the treatment and prophylaxis of influenza. However, not much is known about its adverse effects. The potential side effects were investigated in male and female rats (140-170 g). Oseltamivir was administered at 2.2 mg·kg(-1)·day(-1) for 5 days....See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1139/y11-060
データ提供:米国国立医学図書館(NLM)
Oseltamivir: A Double-Edged Sword in the Fight Against Influenza
This research explores the potential adverse effects of oseltamivir, a widely used antiviral drug for the treatment and prevention of influenza. It's like navigating a desert landscape, where a seemingly helpful oasis can also harbor unexpected dangers. The study investigated the effects of oseltamivir on male and female rats, revealing significant differences in the observed side effects. The findings highlight the importance of understanding the potential risks associated with medications, particularly in the context of sex-specific differences.
Gender Matters: Oseltamivir's Sex-Specific Effects
This study demonstrates that oseltamivir, a commonly used antiviral drug, can have sex-specific effects. It's like navigating a desert landscape, where the terrain can change dramatically depending on the direction you travel. The researchers observed that male rats were more susceptible to the adverse effects of oseltamivir compared to female rats. This finding highlights the importance of considering sex-specific differences when developing and prescribing medications.
Navigating the Desert of Drug Side Effects: A Call for Caution
This research underscores the importance of carefully considering the potential risks associated with medications. It's like navigating a desert, where seemingly benign landmarks can pose unexpected challenges. The study highlights the sex-specific effects of oseltamivir, emphasizing the need for further investigation into the potential risks of this drug. This knowledge can help healthcare providers make informed decisions about the use of oseltamivir, minimizing the risk of adverse effects.
Dr. Camel's Conclusion
This research offers a valuable reminder that medications can have unintended consequences. It's a reminder that even in the seemingly familiar desert of medicine, new discoveries can reshape our understanding of established treatments. The findings highlight the importance of considering sex-specific differences when developing and prescribing medications, ensuring that treatments are as safe and effective as possible.
Date :
- Date Completed 2016-05-05
- Date Revised 2015-08-05
Further Info :
Related Literature
English
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