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Antiinflammatory effects of traditional Korean medicine, JinPi-tang and its active ingredient, hesperidin in HaCaT cells.

Author: KimHyung-Mim, MoonPhil-Dong

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

JinPi-tang (JPT) and its active ingredient, hesperidin (HES), are used in dermatological therapies and cosmeceuticals. This study investigated the anti-inflammatory effects of JPT and HES in HaCaT cells. Both JPT and HES inhibited the production of inflammatory cytokines and the activation of key signaling pathways involved in inflammation. The findings suggest that JPT and HES may be beneficial in treating UV radiation-induced inflammatory skin diseases.
Paper Details　
Original Abstract of the Article :
A traditional Korean medicine, JinPi-tang (JPT), has been used in dermatological therapeutics and cosmeceuticals including antiaging creams and moisturizers. However, it has not been clarified how JPT and its active ingredient, hesperidin (HES), regulates inflammatory reactions in HaCaT cells. Thus,...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1002/ptr.3627

データ提供：米国国立医学図書館（NLM）

JinPi-tang and Hesperidin: A Traditional Korean Medicine with Anti-Inflammatory Potential

Traditional Korean medicine has a rich history, and this study investigates the anti-inflammatory properties of JinPi-tang (JPT) and its active ingredient, hesperidin (HES), in HaCaT cells. The researchers explored the mechanisms by which JPT and HES regulate inflammatory reactions, evaluating their effects on the production of inflammatory mediators and the activation of key signaling pathways.

Unlocking the Secrets of Traditional Medicine: Exploring the Anti-Inflammatory Potential of JinPi-tang

The study found that JPT and HES effectively inhibited the production of inflammatory mediators, such as interleukin-8 and tumor necrosis factor-α, in HaCaT cells. Furthermore, the researchers observed that JPT and HES suppressed the activation of key signaling pathways involved in inflammation, such as nuclear factor-κB, IκBα, and p38 mitogen-activated protein kinase.

The Promise of Traditional Remedies: A Journey Towards Better Health

As a camel researcher, I appreciate the value of exploring traditional remedies, just as a camel relies on its instincts to find nourishment and hydration in the desert. This study highlights the potential of JinPi-tang and hesperidin for treating inflammatory skin diseases, suggesting that traditional medicine may hold valuable solutions for modern health challenges.

Dr.Camel's Conclusion

This study provides evidence for the anti-inflammatory properties of JinPi-tang and its active ingredient, hesperidin, in HaCaT cells. The findings suggest that these traditional remedies could have therapeutic potential for treating inflammatory skin diseases. Just as a camel can navigate the desert with the guidance of ancient wisdom, so too can we learn from the wisdom of traditional medicine to address modern health challenges.

Date :
  1. Date Completed 2013-10-17
  2. Date Revised 2016-11-25
Further Info :

Pubmed ID

21984511

DOI: Digital Object Identifier

10.1002/ptr.3627

SNS
PICO Info
in preparation
Languages

English

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