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Differences in side effects between a conventional carbamazepine preparation and a slow-release preparation of carbamazepine.
Author: Ben-MenachemE, BengtssonE, HeinonenE, PerssonL I
Original Abstract of the Article :
The aim of this double-blind cross-over study was to investigate whether side effects of carbamazepine (CBZ) could be reduced by using a slow-release CBZ preparation. Twenty-one adult patients with epilepsy who had side effects related to the use of CBZ took part in the trial. Patients were randomiz...See full text at original site
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引用元:
https://doi.org/10.1016/0920-1211(90)90088-d
データ提供:米国国立医学図書館(NLM)
Slow-Release Carbamazepine: A Desert Oasis of Reduced Side Effects
Carbamazepine is a commonly used medication for epilepsy, but it can sometimes cause side effects. This research investigates whether a slow-release formulation of carbamazepine can reduce the incidence of side effects compared to a conventional preparation. The study involved a double-blind crossover design, where patients with epilepsy who experienced side effects from carbamazepine were randomly assigned to receive either a conventional or slow-release preparation for three months. The researchers carefully monitored the patients for side effects, including systemic toxicity and neurotoxicity, to determine the impact of the different formulations.
A Desert Oasis of Comfort: Slow-Release Carbamazepine and Side Effects
The research reveals that a slow-release preparation of carbamazepine significantly reduces the severity of neurotoxic side effects compared to a conventional preparation. The study found that patients receiving the slow-release formulation experienced fewer headaches, dizziness, and disturbances of vision, speech, and coordination. This finding suggests that a slow-release formulation may provide a more comfortable and well-tolerated treatment option for individuals with epilepsy who are sensitive to carbamazepine's side effects.
Navigating the Desert of Epilepsy Treatment: Finding the Right Formulation
This research highlights the importance of considering different formulations of carbamazepine to optimize treatment for individuals with epilepsy. The study suggests that a slow-release formulation can minimize the incidence of neurotoxic side effects, providing a more comfortable and effective treatment option for patients. As with any medication, it's important to discuss treatment options and potential side effects with a healthcare professional to find the best approach for individual needs.
Dr. Camel's Conclusion
This research provides a valuable oasis of knowledge for navigating the complexities of epilepsy treatment. The study highlights the potential benefits of using a slow-release formulation of carbamazepine to minimize side effects and enhance patient comfort. This research underscores the importance of considering individual needs and preferences when selecting the most appropriate treatment approach for epilepsy.
Date :
- Date Completed 1990-09-25
- Date Revised 2019-09-12
Further Info :
Related Literature
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