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Pharmacotherapy of chronic kidney disease and mineral bone disorder.

Author: BarretoFellype Carvalho, JorgettiVanda, OliveiraRodrigo Bueno, de OliveiraRodrigo Azevedo

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

The treatment paradigm for CKD-mineral bone disorder has shifted with the introduction of noncalcium-containing phosphate binders, vitamin D receptor activators, and calcimimetics.
Paper Details　
Original Abstract of the Article :
Disturbances of the bone and mineral metabolism are a common complication of chronic kidney disease (CKD); these disturbances are known as CKD-mineral bone disorder (CKD-MBD). A better understanding of the pathophysiological mechanisms of CKD-MBD, along with its negative impact on other organs and s...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1517/14656566.2011.626768

データ提供：米国国立医学図書館（NLM）

Pharmacotherapy of Chronic Kidney Disease and Mineral Bone Disorder

This research delves into the [pharmacological] management of [chronic kidney disease (CKD)] and its associated [mineral bone disorder (CKD-MBD)]. This study utilizes a [review] approach to discuss the [pathophysiology] and [treatment] of [CKD-MBD]. The authors discuss the evolution of [phosphate binder] therapy, highlighting the emergence of [noncalcium-containing phosphate binders] as alternative treatments to avoid [calcium overload]. The study also explores the use of [vitamin D receptor activators] and [calcimimetics] in managing [secondary hyperparathyroidism].

Advances in CKD-MBD Treatment

This research highlights the ongoing advancements in the treatment of [CKD-MBD]. The study underscores the importance of [early intervention] and [personalized therapy] for [CKD-MBD], tailoring treatment strategies to address the unique needs of each patient.

Health Implications and Practical Applications

This research provides valuable insights for healthcare professionals involved in the management of [CKD] and [CKD-MBD]. It emphasizes the need for a [multidisciplinary approach] to care for these patients, involving nephrologists, endocrinologists, and other specialists as needed.

Dr. Camel's Conclusion

Just like a camel needs to adapt to the changing landscape of the desert, healthcare professionals need to stay abreast of the latest advancements in managing [CKD] and [CKD-MBD]. This research provides a valuable overview of the current treatment paradigm, highlighting the importance of personalized therapy and a multidisciplinary approach to optimize patient outcomes.

Date :
  1. Date Completed 2012-02-28
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

22017388

DOI: Digital Object Identifier

10.1517/14656566.2011.626768

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Languages

English

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