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Role of etravirine in the management of treatment-experienced patients with human immunodeficiency virus type 1.

Author: VianiRolando M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Etravirine, a second-generation HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI), is used in combination therapy for treatment-experienced patients with NNRTI-resistant HIV-1. Compared to first-generation NNRTIs, etravirine has a higher genetic barrier to resistance and is better tolerated, with a safety profile similar to placebo except for mild, self-limiting rash. Clinical trials showed superior antiviral activity and improved outcomes compared to control regimens.
Paper Details　
Original Abstract of the Article :
Etravirine is an oral diarylpyrimidine compound, a second-generation human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitor (NNRTI) with expanded antiviral activity against NNRTI-resistant HIV-1, to be used in combination therapy for treatment-experienced patients...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218688/

データ提供：米国国立医学図書館（NLM）

Etravirine: A New Oasis for Treatment-Experienced HIV Patients

This study explores the role of etravirine in managing HIV infection in patients who have already been treated with other medications. Think of this new drug as a newly discovered oasis in the vast and challenging desert of HIV treatment.

A New Hope for Treatment-Experienced Patients: Etravirine

Etravirine is a powerful antiviral drug that can help control HIV infection in patients who have developed resistance to other medications. This is like finding a new oasis in the desert of HIV treatment, offering a lifeline to patients who have exhausted other options.

Navigating the Desert of HIV Treatment: Finding a Safe Oasis

The study emphasizes the importance of selecting the right treatment for each individual patient. Just like navigating a complex desert landscape, it's crucial to choose the right path based on individual needs and circumstances. The study provides valuable information to help healthcare providers make informed decisions about using etravirine in HIV treatment.

Dr.Camel's Conclusion

This study provides a valuable contribution to the ongoing fight against HIV. It's like finding a new oasis in the desert of HIV treatment, offering hope for a better future for patients who have struggled with this challenging disease. The study highlights the importance of continued research and development to create effective and safe treatments for HIV.

Date :
  1. Date Completed 2011-11-23
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

22096392

DOI: Digital Object Identifier

PMC3218688

Related Literature

Article Analysis
・Side Effects of etravirine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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