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An open-label, multicenter study of the efficacy and safety of a weekday/weekend treatment regimen with calcitriol ointment 3 microg/g and clobetasol propionate spray 0.05% in the management of plaque psoriasis.

Author: ColónLuz E, GottschalkRonald, HudsonCharles P, JohnsonLori A, KempersSteven, MenterAlan, PappKim, SmithStacy, SofenHoward

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This open-label study evaluated a weekday/weekend regimen of calcitriol ointment 3 microg/g and clobetasol propionate spray 0.05% for moderate plaque psoriasis. The regimen was effective and well-tolerated, demonstrating the potential for combination therapy to manage psoriasis.
Paper Details　
Original Abstract of the Article :
High-potency topical corticosteroids are the cornerstone of psoriasis therapy. Although highly effective, long-term use of topical steroids can cause adverse side effects. Additionally, steroids alone do not address the multiple pathophysiologic factors that cause the disease. Psoriasis regimens tha...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/22106730

データ提供：米国国立医学図書館（NLM）

Treating Plaque Psoriasis: A Weekday/Weekend Regimen

Psoriasis is a chronic skin condition that affects millions of people, causing itchy, scaly patches that can be both physically and emotionally challenging. Think of it like a desert sandstorm—unpredictable, persistent, and often difficult to manage. Researchers are always searching for effective and safe treatments for this condition, and this study explores a unique approach using a combination of topical medications.

A New Approach to Psoriasis Management

The study involved a weekday/weekend treatment regimen using calcitriol ointment and clobetasol propionate spray, targeting different aspects of the disease. The results demonstrate the effectiveness and tolerability of this regimen for moderate plaque psoriasis, offering a potential new way to manage this chronic condition.

Finding Relief in the Desert

This study suggests that a carefully tailored approach using a combination of medications can help to manage the symptoms of psoriasis, potentially offering a more effective and comfortable treatment option for individuals with this condition. It's like finding a cool breeze in the middle of a desert—a welcome relief from the discomfort and frustration of psoriasis.

Dr.Camel's Conclusion

This study provides evidence for the potential benefits of a weekday/weekend treatment regimen for psoriasis. The approach offers a more targeted and effective treatment option, showcasing the importance of individualized care and exploring innovative solutions for chronic skin conditions.

Date :
  1. Date Completed 2011-12-14
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

22106730

DOI: Digital Object Identifier

22106730

Related Literature

Article Analysis
・Side Effects of calcitriol topical
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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