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Alendronate in the prevention of collapse of the femoral head in nontraumatic osteonecrosis: a two-year multicenter, prospective, randomized, double-blind, placebo-controlled study.
Author: ChangChih-Hao, ChangJe-Ken, ChenChung-Hwan, HouSheng-Mou, LaiKuo-An, WangGwo-Jaw
Original Abstract of the Article :
Osteonecrosis is one of the major debilitating skeletal disorders. Most patients with osteonecrosis of the femoral head eventually need surgery, usually total hip arthroplasty (THA), within a few years of onset. Previous studies showed that alendronate has a pharmacologic effect in reducing osteocla...See full text at original site
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引用元:
https://doi.org/10.1002/art.33498
データ提供:米国国立医学図書館(NLM)
Alendronate: A Potential Solution for Femoral Head Collapse
This research explores the potential benefits of alendronate in preventing femoral head collapse in patients with nontraumatic osteonecrosis. The study, employing a multicenter, prospective, randomized, double-blind, placebo-controlled design, compared the effects of alendronate to placebo. The researchers meticulously monitored the cumulative incidence of total hip arthroplasty (THA) and the time to event after treatment. Their findings provide valuable insights into the potential of alendronate in managing osteonecrosis and delaying the need for THA.Alendronate: A Bone-Strengthening Strategy
The study showed that alendronate significantly reduced the incidence of femoral head collapse and delayed the need for THA compared to placebo. These findings highlight the potential of alendronate in preserving joint function and improving long-term outcomes for patients with osteonecrosis, offering a promising avenue for disease management.Protecting Your Bones: A Step Towards Better Health
This research underscores the importance of exploring novel therapeutic approaches for managing osteonecrosis. The study’s findings on alendronate provide valuable insights into the potential for bone-strengthening strategies, paving the way for future research and clinical applications. It's like finding a sturdy camel to help you traverse the desert of osteonecrosis.Dr. Camel's Conclusion
This study offers a glimmer of hope for patients facing the debilitating effects of osteonecrosis. The findings suggest that alendronate could be a valuable tool in preventing femoral head collapse, preserving joint function, and delaying the need for invasive surgery. It's like finding a hidden oasis of bone health in the desert of osteonecrosis.Date :
- Date Completed 2012-07-13
- Date Revised 2022-04-10
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