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Effects of bepotastine and fexofenadine on histamine-induced flare, wheal and itch.

Author: FukuokaMiyuki, IkomaAkihiko, KabashimaKenji, MiyachiYoshiki, TanizakiHideaki

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Urticaria, or hives, is caused by histamine release from mast cells. This study discusses the use of antihistamines for the treatment of urticaria, specifically focusing on the need for rapidly acting agents.
Paper Details　
Original Abstract of the Article :
Urticaria is mainly caused by mast cell-derived histamine through the histamine H(1) receptor. Antihistamines are occasionally used on demand upon a recurrence of urticaria; therefore, rapidly acting agents should be explored. The onset of action is assumed to depend on time to maximum concentration...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1159/000330663

データ提供：米国国立医学図書館（NLM）

Fast-Acting Antihistamines for Urticaria: A Race Against Time

Urticaria, a common skin condition characterized by itchy welts, can be a frustrating and uncomfortable experience. This study explores the potential of fast-acting antihistamines to effectively manage this condition.

Speeding Up Relief

The researchers investigated the effects of bepotastine and fexofenadine, two antihistamines, on histamine-induced flare, wheal, and itch in patients with urticaria. The authors emphasize the need for rapidly acting agents to effectively treat the symptoms of urticaria, much like a traveler seeking respite from a scorching desert sun.

Improving Urticaria Management

This research highlights the importance of developing antihistamines with a rapid onset of action to provide quicker relief to patients with urticaria. By understanding the factors that influence the speed of action, we can develop more effective treatments for this common condition.

Dr.Camel's Conclusion

The search for fast-acting antihistamines is an important endeavor in the field of urticaria treatment. It's like finding a cool breeze in a desert, offering a sense of relief and comfort to those affected by this condition.

Date :
  1. Date Completed 2012-08-14
  2. Date Revised 2017-11-16
Further Info :

Pubmed ID

22286689

DOI: Digital Object Identifier

10.1159/000330663

Related Literature

Article Analysis
・Effects of fexofenadine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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