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[Treatment of 100 acute myeloid leukemias (author's transl)].

Author: BryonP A, CoiffierB, Favre-GillyJ, FelmanP, FièreD, MartinC, RevolL, Vu VanH

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A study of 100 patients with acute myeloid leukemia found that 68 achieved complete remission (CR). The median duration of CR was 12 months and the median survival time was 13 months overall. Patients under 65 had a median survival time of 15 months, while those over 65 had a median survival of 3 months. Patients in CR had a median survival time of 22 months. The addition of BCG treatment appeared to slightly improve survival.
Paper Details　
Original Abstract of the Article :
Between november 1974 and august 1976, 100 acute myeloïd leukemias were treated by the same protocol L. 275. Induction treatment was daunorubicine, vincristine, cytosine arabinoside, in one intensive course for patients under 65 and cyclophosphamide (CPM), VCR and CAR in a less intensive and repetit...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/224478

データ提供：米国国立医学図書館（NLM）

Treatment of Acute Myeloid Leukemia: A Study of 100 Patients

Acute myeloid leukemia (AML) is a serious blood cancer, like a raging sandstorm that can quickly overwhelm the body's defenses. This study investigated different treatment strategies for AML, analyzing the outcomes of 100 patients.

Treatment Strategies and Outcomes in AML

The study examined different treatment regimens for AML, including chemotherapy and immunotherapy with BCG. The researchers found that while chemotherapy achieved complete remission in a significant proportion of patients, the median survival time was still relatively short. The study also suggested a potential benefit of BCG immunotherapy in improving survival rates.

Navigating the Challenges of Leukemia Treatment

This study highlights the ongoing challenges in treating AML. It emphasizes the need for ongoing research to develop more effective and long-lasting treatment options. It also underscores the importance of individualized treatment plans and the need for careful monitoring and supportive care for patients with this complex disease.

Dr. Camel's Conclusion

This study provides valuable insights into the challenges and complexities of AML treatment. The search for effective therapies continues, just as a camel persistently seeks a source of water in a vast and unforgiving desert. This research offers hope for the future, reminding us that even the most formidable obstacles can be overcome with dedication and perseverance.

Date :
  1. Date Completed 1979-10-26
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

224478

DOI: Digital Object Identifier

224478

SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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