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Prevalence and clinical relevance of enteropathy associated with systemic autoimmune diseases.
Author: AlmagroPere, AlsinaMontserrat, CarrascoAnna, EsteveMaria, Fernández-BañaresFernando, LorasCarme, MarinéMeritxell, Rodriguez-CarballeiraMónica, SalasAntonio, ViverJosep M, VivesMaria-José
Original Abstract of the Article :
OBJECTIVE: To assess whether systemic autoimmune diseases are a risk group for coeliac disease and if there is a systemic autoimmune diseases-associated enteropathy. METHODS: 183 patients with systemic autoimmune diseases were included. Duodenal biopsy was carried out on patients with positive coel...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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引用元:
https://doi.org/10.1016/j.dld.2012.02.013
データ提供:米国国立医学図書館(NLM)
Enteropathy in Systemic Autoimmune Diseases: A Hidden Connection
Systemic autoimmune diseases (SAIDs) are a group of disorders that affect multiple organs and systems. This study delves into the intriguing connection between SAIDs and enteropathy, a condition that affects the small intestine. The researchers aimed to determine whether SAIDs increase the risk of coeliac disease and whether there is a specific enteropathy associated with SAIDs.
The researchers analyzed data from a large cohort of individuals with SAIDs. They performed duodenal biopsies on patients who met specific criteria, including positive coeliac genetics, serology, or symptoms. They carefully examined the biopsies for signs of enteropathy and investigated potential causes, including gluten sensitivity. It's like exploring a hidden oasis in the vast desert of autoimmune disease, uncovering new connections and understanding the interplay of different conditions.
A Complex Landscape: Understanding the Link Between SAIDs and Enteropathy
The study found that the prevalence of coeliac disease with atrophy was low in their cohort, but a significant proportion of patients had lymphocytic enteropathy. However, the clinical relevance of this enteropathy was unclear in many cases. This finding suggests that SAIDs might be associated with a specific enteropathy, but further research is needed to understand its implications for patient management. It's a reminder that the desert of autoimmune disease is a complex and enigmatic landscape, requiring continued exploration to unravel its mysteries.
Living with SAIDs: The Importance of Comprehensive Care
The study emphasizes the importance of a comprehensive approach to managing SAIDs, considering the potential for gastrointestinal involvement. Healthcare providers should be aware of the possibility of enteropathy in patients with SAIDs and consider appropriate investigations and management strategies. It's a reminder that the desert of SAIDs is a vast and diverse landscape, requiring a multi-faceted approach to provide the best possible care for patients.
Dr.Camel's Conclusion
This study sheds light on the complex relationship between systemic autoimmune diseases and enteropathy. It's a reminder that the desert of autoimmune disease is full of hidden connections, and continued research is crucial for understanding the full spectrum of this group of disorders and providing optimal care for affected individuals.
Date :
- Date Completed 2013-01-14
- Date Revised 2022-03-11
Further Info :
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