Paper Details

  1. Home
  2. Paper Details

[Therapeutic management of purulent meningitis in children. Report of 101 cases].

Author:

English AbstractA summary of a research paper/publication written in English for a wider audience.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study examined the treatment of 101 children with uncomplicated bacterial meningitis. All patients initially received a third-generation cephalosporin until bacterial testing was available, at which point some patients continued on this treatment and others switched to ampicillin. Intravenous treatment was stopped after 10 days, regardless of fever. The study found that both treatment approaches were effective, with similar rates of complications. The study also found that phenobarbital was effective in preventing seizures in young children. This study suggests that a simplified treatment approach for uncomplicated meningitis is possible, with initial treatment using a third-generation cephalosporin, switching to ampicillin or amoxicillin based on testing results, discontinuing IV treatment after 10 days, and using phenobarbital to prevent seizures in young children.
Paper Details　
Original Abstract of the Article :
One hundred and one cases of purulent meningitis without any sign of immediate severity have been prospectively treated. Cefotaxime was given until the results of bacteriological tests; when possible, a randomisation separated one group in which cefotaxime was continued and another group in which ce...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/2256787

データ提供：米国国立医学図書館（NLM）

Managing Purulent Meningitis in Children: A Comprehensive Approach

Purulent meningitis, a serious infection of the brain and spinal cord, can be particularly challenging in children. This study prospectively analyzed 101 cases of purulent meningitis in children without any signs of immediate severity. The researchers investigated the effectiveness of cefotaxime, a third-generation cephalosporin, as an initial treatment and evaluated the potential for substituting it with ampicillin. They also explored the role of phenobarbitone in preventing convulsions, particularly in young children. The results suggest that cefotaxime is a suitable initial treatment for purulent meningitis in children. Furthermore, the study supports the use of phenobarbitone for preventing convulsions, particularly in infants.

Simplified Treatment Approach: A Path to Recovery

Based on the study's findings, the authors propose a simplified treatment approach for purulent meningitis in children with typical clinical presentations. This approach includes initiating treatment with a third-generation cephalosporin, such as cefotaxime, and transitioning to ampicillin or amoxicillin once bacterial test results become available. They also advocate for discontinuing intravenous treatment by day 10 without further cerebrospinal fluid control, and the use of phenobarbitone during the acute stage of meningitis to prevent convulsions in young children.

Purulent Meningitis: A Complex Journey Through the Brain

Purulent meningitis is a serious infection that can be likened to a fierce sandstorm raging through the brain. This study offers a roadmap for navigating this treacherous terrain, providing a comprehensive approach to treatment, including the use of powerful antibiotics and preventive measures like phenobarbitone. Remember, it's crucial to consult with a medical professional for prompt and accurate diagnosis and treatment of this condition.

Dr.Camel's Conclusion

This study provides valuable insights into managing purulent meningitis in children. The researchers have devised a streamlined approach to treatment that includes appropriate antibiotic therapy and preventive measures. Just as a camel can navigate a sandstorm with its innate resilience, this research provides a guide for navigating this challenging medical journey.

Date :
  1. Date Completed 1991-01-23
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2256787

DOI: Digital Object Identifier

2256787

Related Literature

Article Analysis
・Effective treatment of meningitis
SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.