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The effect of combined therapy with deferoxamine and deferiprone on serum ferritin level of beta-thalassemic patients.
Author: JahaziAzam, MirbehbahaniNarges, Rahim AbadHanif Hashem Nejad
Original Abstract of the Article :
OBJECTIVE: To determine the effect of combined therapy with deferoxamine and deferiprone on serum ferritin level of beta-thalassemic patients. METHOD AND MATERIALS: This controlled clinical trial was conducted on 26 major beta-thalassemic patients. Twelve patients in case group received deferiprone...See full text at original site
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引用元:
https://doi.org/10.1179/102453312X13376952196610
データ提供:米国国立医学図書館(NLM)
Combating Iron Overload: A Collaborative Approach for Beta-Thalassemia
In the complex world of hematology, beta-thalassemia presents a significant challenge, often leading to iron overload. This condition can have devastating consequences for patients, requiring vigilant management to prevent organ damage. This study explores the effectiveness of combining deferoxamine and deferiprone, two iron chelating agents, in treating beta-thalassemia patients. The researchers sought to determine the impact of this combined therapy on serum ferritin levels, a key indicator of iron overload.A Synergistic Approach to Iron Chelation
The study found that combined therapy with deferoxamine and deferiprone significantly reduced serum ferritin levels in beta-thalassemia patients, outperforming the use of deferoxamine alone. While mild side effects such as nausea and arthropathy were observed, the overall safety profile of the combined therapy remained favorable. These findings suggest that combining deferoxamine and deferiprone could offer a promising treatment option for beta-thalassemia patients, effectively managing iron overload and potentially preventing long-term complications.A Beacon of Hope for Beta-Thalassemia Patients
This research offers a glimmer of hope for individuals living with beta-thalassemia. The effectiveness of combined therapy in reducing iron overload holds significant promise for improving patient outcomes and minimizing the risk of organ damage. The study’s findings highlight the importance of personalized treatment approaches in tackling complex medical conditions like beta-thalassemia.Dr.Camel's Conclusion
Just as a camel carries essential supplies across the desert, deferoxamine and deferiprone work in tandem to combat iron overload in beta-thalassemia. This study demonstrates the efficacy and safety of this combined approach, offering a beacon of hope for individuals battling this challenging condition. The findings underscore the importance of individualized treatment strategies in ensuring optimal patient care.Date :
- Date Completed 2013-01-03
- Date Revised 2018-12-01
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