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The management of hyperphosphatemia by lanthanum carbonate in chronic kidney disease patients.

Author: HanbaYoshiyuki, KoreedaDaisuke, MimaToru, NakashimaYuri, NegiShigeo, OhyaMasaki, SakaguchiToshifumi, ShigematsuTakashi, TatsutaKoichi, YamanakaShintaro, YoshimotoWataru

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study discusses the use of lanthanum carbonate, a powerful phosphate (Pi) binder, in the management of hyperphosphatemia in patients with chronic kidney disease. Lanthanum carbonate has a similar effect to aluminum hydroxide in reducing serum Pi levels and is excreted via the liver, making it advantageous for patients with renal failure. While there is 6 years of clinical treatment data on lanthanum carbonate worldwide, there have been 3 years of clinical use in Japanese patients with hyperphosphatemia. No serious side effects have been reported, but further monitoring is recommended.
Paper Details　
Original Abstract of the Article :
Hyperphosphatemia has been shown to be involved not only in the onset and progression of secondary hyperparathyroidism but also in vascular calcification. In addition, it influences the clinical course of patients with chronic kidney disease. Phosphate (Pi) binder is required in the management of hy...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379863/

データ提供：米国国立医学図書館（NLM）

Hyperphosphatemia: A Desert Mirage in Chronic Kidney Disease

The desert of chronic kidney disease (CKD) can be a harsh and unforgiving place, with hyperphosphatemia, an excess of phosphate in the blood, posing a significant challenge for patients. This study, like a group of researchers seeking a solution to this problem, investigates the use of lanthanum carbonate, a phosphate binder, in managing hyperphosphatemia in CKD patients. The authors review the evidence for lanthanum carbonate's efficacy and safety, exploring its potential to improve the health and well-being of CKD patients.

The study, like a careful analysis of the desert's resources, finds that lanthanum carbonate is an effective phosphate binder, significantly reducing serum phosphate levels in CKD patients. This treatment option offers a potential solution to hyperphosphatemia, a condition that can contribute to the progression of CKD and lead to serious health complications.

Managing Hyperphosphatemia: A Crucial Step in CKD Care

This study highlights the importance of managing hyperphosphatemia in CKD patients. It's like providing a camel with a reliable source of water in the desert, allowing it to stay hydrated and healthy. By effectively controlling phosphate levels, healthcare professionals can help patients slow the progression of CKD and improve their overall well-being.

Navigating CKD: A Collaborative Effort

This research emphasizes the importance of a collaborative approach to CKD management. It's like a team of explorers working together to navigate the desert, each member contributing their expertise to ensure the success of the journey. By working closely with healthcare professionals, CKD patients can make informed decisions about their treatment and ensure the best possible outcomes.

Dr.Camel's Conclusion

This study provides compelling evidence for the efficacy of lanthanum carbonate in managing hyperphosphatemia in CKD patients. It's a reminder that even in the most challenging deserts, there are solutions to be found, offering hope for a brighter future for CKD patients.

Date :
  1. Date Completed 2012-10-02
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

22723728

DOI: Digital Object Identifier

PMC3379863

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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