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[Comparative study of potassium-sparing effects of triamterene and amiloride in the treatment with hydrochlorothiazide].

Author: DonskovaT V, GlezerG A, LevinzonA M, LipkoD S, MerzonA K, ShelestIu P

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Hydrochlorothiazide (HCT) combined with triamterene (T) or amiloride (A) is more effective in controlling blood pressure than HCT alone, but may increase potassium levels in some patients.
Paper Details　
Original Abstract of the Article :
Hydrochlorothiazide (HCT), 25 or 50 mg a day, alone and in combination with triamterene (T), 50 and 100 mg, respectively, or amiloride (A), 2.5 and 5 mg, respectively, was examined for effects on daily urinary potassium and sodium excretion. Daily sodium excretion was increased 1.5-2-fold with a dou...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2290332

データ提供：米国国立医学図書館（NLM）

Potassium-Sparing Effects of Triamterene and Amiloride: Navigating the Desert of Electrolyte Balance

Electrolyte balance, like a carefully maintained desert oasis, is crucial for maintaining bodily functions. This study, like a group of researchers carefully studying the dynamics of a desert ecosystem, investigated the potassium-sparing effects of two diuretic drugs, triamterene and amiloride, when combined with hydrochlorothiazide (HCT).

A Closer Look at Potassium-Sparing Effects

The study, like a meticulous desert explorer, carefully analyzed urinary potassium and sodium excretion in patients receiving different combinations of diuretics. The findings revealed that amiloride, compared to triamterene, showed a slightly higher potassium-sparing effect, suggesting that amiloride might be a more effective option for maintaining potassium balance.

Maintaining the Oasis of Electrolyte Balance

This research offers valuable insights into the potassium-sparing effects of diuretics, highlighting the importance of carefully considering the individual needs of patients and choosing the most appropriate combination to maintain electrolyte balance.

Dr.Camel's Conclusion

This study underscores the importance of electrolyte balance, reminding us that like a desert oasis, our bodies require careful maintenance to thrive. The findings provide valuable guidance for healthcare providers, helping them to choose the most appropriate diuretic combinations to maintain optimal electrolyte balance and prevent complications.

Date :
  1. Date Completed 1991-04-04
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2290332

DOI: Digital Object Identifier

2290332

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・Effects of triamterene
SNS
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in preparation
Languages

Russian

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