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Serum 25-hydroxyvitamin D response to vitamin D3 supplementation 50,000 IU monthly in youth with HIV-1 infection.

Author: , FlynnPatricia, HavensPeter L, HazraRohan, KapogiannisBill G, Lujan-ZilbermannJorge, MulliganKathleen, RutledgeBrandy, StephensenCharles B, Van LoanMarta D, WilsonCraig M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Supplementation with vitamin D(3) 50,000 IU monthly for three doses was safe and increased 25-OHD serum concentration from a baseline of 21.9 (13.3) to 35.9 (19.1) ng/ml at wk 12 (P < 0.001). Increases in 25-OHD occurred in treated participants regardless of antiretroviral regimen.
Paper Details　
Original Abstract of the Article :
CONTEXT: Vitamin D deficiency and insufficiency occur frequently in youth with HIV infection, particularly among those receiving the antiretroviral drug efavirenz. Optimal vitamin D dosing for treatment is unclear. OBJECTIVE: Our objective was to evaluate safety and measure change in 25-hydroxyvita...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485594/

データ提供：米国国立医学図書館（NLM）

Vitamin D Supplementation in Youth with HIV-1 Infection

This randomized, double-blind, placebo-controlled study investigates the efficacy and safety of vitamin D3 supplementation in HIV-infected youth. The study found that monthly supplementation with 50,000 IU of vitamin D3 was safe and effectively increased serum 25-hydroxyvitamin D (25-OHD) concentration, regardless of antiretroviral regimen. These findings suggest that vitamin D supplementation can be a valuable strategy for managing vitamin D deficiency in HIV-infected youth.

Effective Vitamin D Supplementation for HIV-Infected Youth

The research demonstrates the effectiveness of vitamin D supplementation in improving vitamin D status in HIV-infected youth. The study found that monthly supplementation with 50,000 IU of vitamin D3 safely and effectively increased serum 25-hydroxyvitamin D (25-OHD) concentration. This provides valuable insights for healthcare providers managing HIV-infected youth, highlighting the importance of vitamin D supplementation in optimizing their health.

Optimizing Health Outcomes in HIV-Infected Youth

This study emphasizes the importance of addressing vitamin D deficiency in HIV-infected youth. The study found that vitamin D supplementation can effectively improve vitamin D status and potentially contribute to overall health and well-being. The research encourages a proactive approach to managing vitamin D levels in HIV-infected youth, promoting optimal health outcomes and improving their quality of life.

Dr. Camel's Conclusion

Just as a camel adapts to the harsh desert environment by storing water and seeking out shade, HIV-infected youth can benefit from a proactive approach to managing their health. This research emphasizes the importance of vitamin D supplementation, demonstrating its safety and efficacy in improving vitamin D status. By understanding and addressing the unique needs of HIV-infected youth, healthcare providers can create a supportive and nurturing environment for their well-being, just as a caring camel mother guides her young through the challenges of the desert.

Date :
  1. Date Completed 2013-01-25
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

22933542

DOI: Digital Object Identifier

PMC3485594

Related Literature

Article Analysis
・Effective treatment of vitamin d deficiency
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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