4-Liter split-dose polyethylene glycol is superior to other bowel preparations, based on systematic review and meta-analysis.

Author: EnestvedtBrintha K, FennertyM Brian, LaineLoren A, TierneyAnn, TofaniChristina

Paper Details 
Original Abstract of the Article :
Adequate bowel cleansing is an important determinant of the efficacy of screening colonoscopy. Polyethylene glycol (PEG)-based solutions are used commonly in bowel preparation, but their poor palatability and large volumes (4 L) influence compliance. Adjunct therapies, such as bisacodyl, split-dose ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1016/j.cgh.2012.08.029

データ提供:米国国立医学図書館(NLM)

Preparing for Colonoscopy: A Quest for Optimal Bowel Cleansing

Adequate bowel cleansing is essential for accurate results during colonoscopy. Polyethylene glycol (PEG)-based solutions are commonly used for bowel preparation, but their large volumes and unpleasant taste can hinder compliance. This meta-analysis delves into the effectiveness of different PEG-based bowel preparation regimens, focusing on the impact of split-dose regimens and lower-volume regimens.

Split-Dose Regimen: A Potential Advantage

The meta-analysis found that a 4-L split-dose regimen of PEG was superior to other bowel preparation methods, including single-dose regimens, bisacodyl-assisted regimens, and lower-volume regimens. This suggests that a split-dose approach may improve bowel cleansing efficacy, possibly by reducing the burden of fluid intake and promoting better patient tolerance.

Improving Colonoscopy Experience: A Focus on Patient Comfort

The findings highlight the importance of optimizing bowel preparation regimens to improve patient comfort and compliance. Further research is needed to explore the optimal split-dose regimen and identify other factors that contribute to successful bowel cleansing.

Dr.Camel's Conclusion

Navigating the journey to a successful colonoscopy can be a bit like traversing a sandy desert. Finding the right preparation regimen is crucial to ensure a smooth and effective experience. This research sheds light on the potential benefits of split-dose PEG regimens, offering a more comfortable and potentially more effective way to prepare for this important diagnostic procedure.

Date :
  1. Date Completed 2013-03-22
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

22940741

DOI: Digital Object Identifier

10.1016/j.cgh.2012.08.029

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.