Antiangiogenic effects of axitinib, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, on laser-induced choroidal neovascularization in mice.

Author: ChoWon-Kyung, ChoiHyun-Su, KangSeungbum, KimSo-Hee, ParkKi Cheol, RohChang Rae, RohYoung-Jung, YangKeum-Jin

Paper Details 
Original Abstract of the Article :
PURPOSE: To investigate the effects of axitinib, an inhibitor of vascular endothelial growth factor receptors, on choroidal neovascularization (CNV) in an animal model of neovascular age-related macular degeneration (AMD). METHODS: Experimental CNV lesions were induced in C57BL/6 mice by laser phot...See full text at original site
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引用元:
https://doi.org/10.3109/02713683.2012.727520

データ提供:米国国立医学図書館(NLM)

Antibiotic Coverage for Community-Acquired Pneumonia

This study delves into the complex world of antibiotics for community-acquired pneumonia (CAP), a condition that can feel like a sandstorm swirling through your lungs. The research explores the common practice of using broad-spectrum antibiotics for CAP, a practice that might be akin to a camel navigating the desert with a heavy pack. The study suggests that limiting the initial antibiotic coverage to specific pathogens could be more efficient and reduce the risk of resistance. The authors call for more evidence-based guidelines for treating CAP, advocating for a more targeted approach, much like a camel finding a specific oasis in the vast desert.

Targeting the Right Oasis

The study suggests that a more targeted approach to antibiotic therapy for CAP could be beneficial. Just as a camel seeks out a specific oasis for water and sustenance, doctors need to pinpoint the specific pathogen causing the pneumonia to prescribe the most effective antibiotic. This approach could help minimize the risk of resistance and reduce unnecessary antibiotic use.

Navigating the Desert of Infection

This research emphasizes the importance of responsible antibiotic use. Just as a camel conserves its water supply in the desert, we must be mindful of our antibiotic resources to prevent resistance. The findings encourage further research and development of more effective and targeted therapies for CAP, ultimately leading to better outcomes for patients.

Dr. Camel's Conclusion

This study highlights the importance of evidence-based guidelines for antibiotic use in community-acquired pneumonia. Just as a camel navigates the desert with a keen sense of direction, doctors need to use their knowledge and resources to select the most effective antibiotics for their patients. This research underscores the need for careful consideration of antibiotic coverage, ensuring we use these vital resources wisely.

Date :
  1. Date Completed 2013-06-04
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

23013553

DOI: Digital Object Identifier

10.3109/02713683.2012.727520

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Languages

English

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