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Evaluation of the neurological safety of epidural milnacipran in rats.

Author: KangHyun, KangKyung Ho, KimBaek Hui, LeeSang Chul, LimSeung Mo, LimYoung Jin, NahmFrancis Sahngun, ShinHwa Yong, ShinMee Ran

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study examined the neurotoxicity of epidural milnacipran in rats. No neurotoxicity was observed, suggesting that epidural administration of milnacipran may be safe.
Paper Details　
Original Abstract of the Article :
Milnacipran is a balanced serotonin norepinephrine reuptake inhibitor with minimal side effects and broad safety margin. It acts primarily on the descending inhibitory pain pathway in brain and spinal cord. In many animal studies, intrathecal administration of milnacipran is effective in neuropathic...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468799/

データ提供：米国国立医学図書館（NLM）

The Neurological Safety of Epidural Milnacipran in Rats: A Journey Through the Desert of Knowledge

The world of medicine is a vast desert, full of mysteries to be uncovered. One such mystery is the neurological safety of epidural milnacipran in rats. This research, like a camel traversing the desert sands, delves into this very important question, using [research methodology] to explore [research objectives]. The authors discovered [main findings] and their implications for the field of [research field]. A particularly noteworthy finding is [remarkable results or significance].

Unraveling the Neurological Safety of Epidural Milnacipran

This study, like a compass guiding a caravan across the desert, sheds light on the potential neurological impact of epidural milnacipran in rats. The results suggest that [social implications].

The Importance of Understanding Epidural Milnacipran

As we continue our journey through this vast desert of knowledge, understanding the potential [health benefits or risks] associated with epidural milnacipran is crucial. This information can guide us in making informed decisions about [daily life practices].

Dr. Camel's Conclusion

This research, like a well-placed oasis in the desert, provides us with valuable insights into the neurological safety of epidural milnacipran in rats. It emphasizes the importance of further research in this area, ensuring the safe and effective use of this medication.

Date :
  1. Date Completed 2012-10-24
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

23091683

DOI: Digital Object Identifier

PMC3468799

Related Literature

Article Analysis
・Side Effects of milnacipran
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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