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Switch from etravirine twice daily to once daily in non-nucleoside reverse transcriptase inhibitor (NNRTI)-resistant HIV-infected patients with suppressed viremia: the Monetra study.
Author: AgherR, AssoumouL, BlancC, CabyF, CalvezV, CourbonE, FouratiS, KatlamaC, KtorzaN, MarcelinA G, PeytavinG, SchneiderL, TindelM
Original Abstract of the Article :
BACKGROUND: Etravirine (ETR) is recommended as twice-daily dosing in pretreated patients. There are no data regarding the use of ETR once daily in HIV-experienced patients with prior resistance to first-generation non-nucleoside reverse transcripase inhibitors (NNRTIs). OBJECTIVES: To evaluate the ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1310/hct1305-284
データ提供:米国国立医学図書館(NLM)
Etravirine: A Shifting Sands Treatment for HIV
The treatment landscape for HIV is constantly evolving, with new therapies and dosing regimens emerging to combat this challenging virus. This study explores the feasibility of switching from twice-daily to once-daily dosing of etravirine, a non-nucleoside reverse transcriptase inhibitor (NNRTI), in patients with suppressed viremia. Imagine a desert traveler adjusting their journey to optimize their route – this is what researchers are doing with etravirine dosing. They aimed to determine if once-daily dosing could maintain viral suppression while simplifying treatment regimens.
Once-Daily Etravirine: A Simpler Path
The study found that once-daily etravirine was effective in maintaining viral suppression in HIV-infected patients with prior experience with NNRTIs. This finding, like a shortcut across the desert, offers a simplified treatment approach for patients. The study also showed that etravirine maintained stable drug levels when administered once daily, a reassuring observation for both patients and physicians.
Health Considerations: Managing HIV
The journey with HIV is complex, and navigating treatment options requires close collaboration between patients and healthcare professionals. This research offers a promising avenue for simplifying treatment regimens, potentially improving adherence and quality of life. Remember, the path to managing HIV is best traveled with expert guidance and support.
Dr.Camel's Conclusion
This research highlights the potential of simplifying HIV treatment by shifting to once-daily dosing of etravirine. The study findings are like discovering a hidden oasis in the desert of HIV management, offering a more convenient and potentially effective approach for patients. The journey toward a cure for HIV may be long, but research continues to pave the way for improved treatments, bringing hope and resilience to those living with this challenging condition.
Date :
- Date Completed 2012-12-11
- Date Revised 2020-12-09
Further Info :
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