A Case of Balsalazide-Induced Limited Form of Granulomatosis with Polyangiitis with Bronchiolitis Obliterans Organizing Pneumonia-like Variant in Ulcerative Colitis.

Author: HaSeung Yeon, JangYoung Rock, KangShin Myung, KimEun Young, KimSuji, ParkJeong-Woong, YoonHyun-Hwa

Paper Details 
Original Abstract of the Article :
5-Aminosalicylate agents are the main therapeutic agents for ulcerative colitis. Balsalazide is a prodrug of 5-aminosalicylate and has fewer side effects than the other 5-aminosalicylate agents. Pulmonary complications resembling granulomatosis with polyangiitis in ulcerative colitis are extremely r...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510283/

データ提供:米国国立医学図書館(NLM)

A Case of Balsalazide-Induced Limited Form of Granulomatosis with Polyangiitis

The field of gastroenterology is constantly challenged by rare and complex cases. This case report presents a unique instance of balsalazide-induced granulomatosis with polyangiitis (GPA), a rare autoimmune disorder. The authors describe a patient with ulcerative colitis who developed respiratory symptoms and multiple pulmonary nodules after being treated with balsalazide. This case highlights the potential for drug-induced autoimmune reactions and the need for careful monitoring of patients receiving medications that can trigger these responses.

Navigating the Unpredictability of Drug-Induced Autoimmune Reactions

This case study serves as a reminder that drug-induced autoimmune reactions can occur even with commonly used medications. The study underscores the importance of vigilance in monitoring patients for potential side effects, especially those receiving medications that can trigger autoimmune responses. This case highlights the need for ongoing research to understand the mechanisms underlying drug-induced autoimmune reactions, enabling clinicians to better identify and manage these potentially life-threatening complications.

Understanding the Complexities of Drug-Induced Autoimmune Reactions

The case report emphasizes the importance of considering the potential for drug-induced autoimmune reactions when evaluating patients presenting with unexplained symptoms. The authors highlight the need for a comprehensive assessment of the patient's medication history and clinical presentation, including a careful consideration of potential drug-induced side effects. This study underscores the need for collaboration between different medical specialties, particularly when investigating complex cases involving potential drug-induced autoimmune reactions.

Dr.Camel's Conclusion

This case report is like a sudden sandstorm in the desert of gastroenterology, highlighting the unpredictable nature of drug-induced autoimmune reactions. The researchers have brought to light the potential for seemingly safe medications to trigger complex autoimmune responses, reminding us that even in the most familiar territory, there can be hidden dangers. By remaining vigilant and prioritizing patient safety, we can navigate this challenging landscape and provide the best possible care for our patients.

Date :
  1. Date Completed 2012-12-12
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

23227073

DOI: Digital Object Identifier

PMC3510283

Related Literature

SNS
PICO Info
in preparation
Languages

English

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