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Methylnaltrexone for the treatment of opioid-induced constipation.
Author: BaderSabine, BeckerGerhild, DürkThorsten
Original Abstract of the Article :
Opioids are the drugs of choice for treating moderate-to-severe pain, especially for patients in the end stage of cancer or other advanced illnesses, and also in critical care or for the treatment of chronic pain. Side effects such as nausea, pruritus, dizziness and constipation have to be controlle...See full text at original site
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1586/egh.12.63
データ提供:米国国立医学図書館(NLM)
Methylnaltrexone: A Beacon of Hope for Opioid-Induced Constipation
Opioids are powerful pain relievers, but they can also cause a range of side effects, including constipation. This study investigates the use of methylnaltrexone, a μ-opioid receptor antagonist, for the treatment of opioid-induced constipation. The researchers provide a comprehensive overview of the pharmacological properties, clinical evidence, and potential future applications of methylnaltrexone. This study uses a review of the existing literature, a valuable tool for synthesizing and evaluating current knowledge on a particular topic.
Methylnaltrexone: A Solution for a Common Problem
The study found that methylnaltrexone is an effective and well-tolerated treatment for opioid-induced constipation. It works by blocking μ-opioid receptors in the gut, relieving constipation without affecting the analgesic effects of opioids. It's like finding a cool spring in the desert of opioid-induced constipation, offering relief and restoring balance. The study highlights the potential of methylnaltrexone to improve the quality of life for patients receiving opioid therapy, allowing them to benefit from pain relief without the debilitating side effects of constipation.
Navigating the Desert of Opioid Therapy: Finding a Path to Comfort
This study provides valuable insights for patients and clinicians seeking to manage opioid-induced constipation. It's like finding a map through the desert of opioid therapy, guiding us towards a more comfortable and effective approach. By understanding the mechanisms of action, clinical evidence, and potential future applications of methylnaltrexone, we can make informed decisions about the best course of treatment for this common and challenging side effect of opioid therapy.
Dr.Camel's Conclusion
This study provides a comprehensive overview of methylnaltrexone, a promising treatment option for opioid-induced constipation. By offering targeted relief from constipation without affecting opioid analgesia, methylnaltrexone can improve the quality of life for patients receiving opioid therapy.
Date :
- Date Completed 2013-06-03
- Date Revised 2022-03-17
Further Info :
Related Literature
English
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