Paper Details 
Original Abstract of the Article :
Parkinson's disease is the second most common neurodegenerative disorder, affecting 1 to 2 percent of people older than 60 years. Recent reviews show that depression is a common and potentially debilitating aspect of Parkinson's disease, affecting 40 to 50 percent of patients. Depression in Parkinso...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552466/

データ提供:米国国立医学図書館(NLM)

Successful Use of Rasagiline in Combination with Antidepressants

The study presents a case report of a 58-year-old woman with Parkinson's disease who successfully received rasagiline in combination with two antidepressants (venlafaxine and bupropion). The researchers highlight the common occurrence of depression in patients with Parkinson's disease and the challenges of pharmacotherapy due to potential side effects and drug interactions. The case report demonstrates the potential benefits of using rasagiline, a novel monoamine oxidase type B (MAO-B) inhibitor, in combination with antidepressants for managing both Parkinson's disease and comorbid depression.

Addressing Depression in Parkinson's Disease

The case report suggests that combining rasagiline with antidepressants may be a viable option for treating depression in Parkinson's disease, particularly in cases where traditional treatments have been ineffective. The successful outcome in this case provides encouraging evidence for further investigation into this therapeutic approach.

Navigating Treatment for Parkinson's Disease

The research highlights the importance of individualized treatment approaches for Parkinson's disease, considering the presence of comorbid conditions such as depression. The case report underscores the need for further research to explore the efficacy and safety of combining rasagiline with antidepressants in managing both Parkinson's disease and depression.

Dr.Camel's Conclusion

Like finding a hidden oasis in the desert, the successful combination of rasagiline and antidepressants offers a glimmer of hope for patients with Parkinson's disease and comorbid depression. This case report provides valuable insights into the potential benefits of this therapeutic approach, underscoring the importance of exploring new treatment options for this complex condition.

Date :
  1. Date Completed 2013-07-04
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

23346517

DOI: Digital Object Identifier

PMC3552466

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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