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Disaccharides in the treatment of hepatic encephalopathy.

Author: SharmaBarjesh Chander, SharmaPraveen

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Lactulose and lactitol, nonabsorbable disaccharides, are considered first-line therapy for the treatment of hepatic encephalopathy (HE) and minimal hepatic encephalopathy (MHE). Combination therapy of disaccharides with rifaximin, L-ornithine L-aspartate, or probiotics needs further validation.
Paper Details　
Original Abstract of the Article :
Management of hepatic encephalopathy (HE) primarily involves avoidance of precipitating factors and administration of various ammonia-lowering therapies such as nonabsorbable disaccharides and antimicrobial agents like rifaximin. The nonabsorbable disaccharides which include lactulose and lactitol a...See full text at original site
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引用元：
https://doi.org/10.1007/s11011-013-9392-4

データ提供：米国国立医学図書館（NLM）

Hepatic Encephalopathy: Finding a Pathway to Clarity

Hepatic encephalopathy (HE) is a serious complication of liver disease, often characterized by cognitive impairment. This study explores the use of nonabsorbable disaccharides, like lactulose and lactitol, in treating HE. The researchers aimed to assess the effectiveness of these disaccharides as a first-line therapy for HE and minimal hepatic encephalopathy (MHE).

Disaccharides: A Beacon of Hope in the Desert of HE

The study found that disaccharides, particularly lactulose, are effective in improving cognitive function and quality of life in patients with HE and MHE. This is like discovering a wellspring of clarity in the desert of HE, helping to restore mental function and well-being. The study also found that lactitol is comparable to lactulose with fewer side effects, offering a more comfortable and manageable treatment option.

Managing HE: A Desert Traveler's Toolkit

If you are diagnosed with HE or MHE, it's crucial to work closely with your doctor to manage your condition. This may involve lifestyle modifications, medications, and close monitoring to minimize the risk of complications. Just as a desert traveler needs to be prepared for the journey, it's important to have a comprehensive plan in place for managing HE and maintaining your overall health.

Dr.Camel's Conclusion

This study offers valuable insights into the management of HE, providing a beacon of hope in the desert of this challenging condition. By understanding the effectiveness of disaccharides and other treatment strategies, we can work to improve the lives of patients with HE and help them navigate this complex journey.

Date :
  1. Date Completed 2013-12-16
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

23456517

DOI: Digital Object Identifier

10.1007/s11011-013-9392-4

Related Literature

Article Analysis
・Side Effects of rifaximin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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