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Levomilnacipran (F2695), a norepinephrine-preferring SNRI: profile in vitro and in models of depression and anxiety.
Author: AssiéM B, AuclairA L, BardinL, CussacD, DepoortèreR, HeuslerP, MarienM, MartelJ C, Newman-TancrediA, O'ConnorJ A
Original Abstract of the Article :
Levomilnacipran (LVM; F2695) is the more active enantiomer of the serotonin/norepinephrine (5-HT/NE) reuptake inhibitor (SNRI) milnacipran and is currently under development for the treatment of major depressive disorder. LVM was benchmarked against two other SNRIs, duloxetine and venlafaxine, in bi...See full text at original site
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引用元:
https://doi.org/10.1016/j.neuropharm.2013.02.024
データ提供:米国国立医学図書館(NLM)
Levomilnacipran: A New Hope in the Desert of Depression and Anxiety
Depression and anxiety are prevalent mental health conditions, affecting millions worldwide. This study introduces levomilnacipran, a new medication under development for the treatment of major depressive disorder. The researchers investigated the pharmacological profile of levomilnacipran, comparing it to other serotonin/norepinephrine reuptake inhibitors (SNRIs), and evaluated its efficacy in preclinical models of depression and anxiety.
Levomilnacipran: A Potential Oasis for Depression and Anxiety
The study found that levomilnacipran exhibited potent activity in preclinical models of depression and anxiety, demonstrating potential for treating these conditions. The medication demonstrated high affinity for serotonin and norepinephrine transporters and exhibited potent inhibition of serotonin and norepinephrine reuptake. Imagine a camel caravan, equipped with a powerful compass, navigating the vast desert of mental health. Levomilnacipran, like a reliable compass, could guide patients toward a brighter future, offering a potential oasis of relief from the distressing symptoms of depression and anxiety.
A Promising Journey in Mental Health
This study suggests that levomilnacipran could be a valuable addition to the treatment options for depression and anxiety. The findings provide hope for those seeking relief from these challenging conditions. It's important to remember that mental health treatment is a personalized journey, and seeking professional help is crucial for finding the most effective path to recovery.
Dr. Camel's Conclusion
The study's findings suggest that levomilnacipran could be a promising treatment option for major depressive disorder, offering a potential oasis of relief for those struggling with depression and anxiety. The medication's potent activity in preclinical models of depression and anxiety provides hope for a more effective approach to treating these challenging conditions. Just as a camel caravan needs a reliable compass to navigate the desert, individuals seeking mental health treatment can benefit from innovative medications like levomilnacipran, offering a brighter path to recovery.
Date :
- Date Completed 2013-11-26
- Date Revised 2018-12-02
Further Info :
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