A randomized, phase I, 3-way crossover study to examine the effects of food on the pharmacokinetics of single doses of 400 mg posaconazole oral suspension in healthy male Taiwanese subjects.

Author: ChangFeng-Yee, LinTe-Yu, YangMin-Hui

Paper Details 
Original Abstract of the Article :
PURPOSE: The pharmacokinetic parameters of a single 400-mg oral dose of posaconazole suspension, administered under fasting and fed conditions, were compared in healthy male Taiwanese volunteers. METHODS: After an overnight fast, 16 subjects received a single oral dose of posaconazole suspension (4...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/23503449

データ提供:米国国立医学図書館(NLM)

Posaconazole: A Journey Through the Digestive System

Posaconazole, an antifungal medication used to treat a range of infections, is like a skilled desert explorer, navigating the intricate pathways of the human body. This study investigates the effects of food on the absorption and effectiveness of posaconazole, aiming to optimize its use and ensure its effectiveness.

The study, conducted by a team of researchers, tested the impact of fasting and different types of meals on the pharmacokinetics of posaconazole. They found that posaconazole absorption was significantly enhanced when taken with food, regardless of the type of meal. This research, like a careful desert traveller choosing the best path through a treacherous landscape, highlights the importance of understanding the effects of food on medication absorption.

Food's Influence on Posaconazole Absorption: A Desert Journey of Understanding

The study's findings suggest that taking posaconazole with a meal, like a desert traveler enjoying a nourishing feast, can improve its absorption and potentially increase its effectiveness. This research provides valuable insights for optimizing posaconazole therapy.

Maximizing Medication Effectiveness: A Journey of Informed Choices

This study emphasizes the importance of considering the effects of food on medication absorption, offering patients a more informed approach to managing their treatment. By understanding the factors that can influence the efficacy of posaconazole, individuals can work with their healthcare providers to make informed choices about their medication regimen, ensuring they receive the optimal benefits from their treatment.

Dr.Camel's Conclusion

This research highlights the importance of food in influencing the absorption of posaconazole, like a desert oasis offering a nourishing respite for weary travelers. Understanding these interactions can help healthcare providers optimize medication regimens and ensure that patients receive the full benefits of their treatment. This study underscores the ongoing journey to understand the complexities of medication absorption and improve patient outcomes.

Date :
  1. Date Completed 2013-12-23
  2. Date Revised 2013-03-18
Further Info :

Pubmed ID

23503449

DOI: Digital Object Identifier

00007691-201304000-00011

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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