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Effects of silodosin, a selective α1A-adrenoceptor antagonist, on bladder blood flow and bladder function in a rat model of atherosclerosis induced chronic bladder ischemia without bladder outlet obstruction.
Author: AikawaKen, GoiYoshiaki, NomiyaMasanori, SagawaKoji, TomiyamaYoshitaka, YamaguchiOsamu
Original Abstract of the Article :
PURPOSE: We investigated the effects of the selective α1A-adrenoceptor antagonist silodosin on bladder blood flow and bladder function in a rat model of atherosclerosis induced chronic bladder ischemia without bladder outlet obstruction. MATERIALS AND METHODS: The chronic bladder ischemia model was...See full text at original site
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引用元:
https://doi.org/10.1016/j.juro.2013.03.110
データ提供:米国国立医学図書館(NLM)
Effects of Silodosin on Bladder Blood Flow and Function in a Rat Model of Atherosclerosis
Imagine a camel with a clogged nose in the middle of a dusty desert. The camel can't breathe properly and is struggling to travel. This is similar to the situation researchers explored in this study. The researchers focused on the effects of silodosin, a medication typically used to treat enlarged prostate, on bladder blood flow and function in a rat model of atherosclerosis. They found that silodosin was able to improve bladder function by restoring blood flow in rats with atherosclerosis. This suggests that silodosin may have potential as a treatment for certain bladder issues related to atherosclerosis, a condition that involves plaque buildup in the arteries.
Silodosin Shows Promise for Improving Bladder Function in Atherosclerosis
The results of this study indicate that silodosin may be a promising therapeutic option for improving bladder function in individuals with atherosclerosis. The study demonstrated that silodosin was effective in restoring blood flow to the bladder and improving bladder function in a rat model. This suggests that silodosin could potentially benefit individuals experiencing bladder dysfunction associated with atherosclerosis.
Be Proactive and Seek Medical Advice
It is crucial to remember that this study was conducted on rats. While promising, more research is needed to confirm the effectiveness and safety of silodosin for human patients with atherosclerosis. If you are experiencing bladder dysfunction, it is essential to consult a healthcare professional. They can determine the underlying cause and recommend the best treatment options for your specific situation. Don't let your bladder health become a desert of discomfort, seek help from a healthcare expert.
Dr. Camel's Conclusion
This research provides a valuable insight into the potential benefits of silodosin for improving bladder function in the context of atherosclerosis. The study's findings warrant further investigation in human subjects to assess its clinical efficacy and safety. This research emphasizes the importance of exploring novel treatments for bladder dysfunction in individuals with atherosclerosis.
Date :
- Date Completed 2013-12-11
- Date Revised 2013-08-12
Further Info :
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