Ameliorative effects of caffeic acid phenethyl ester on an eccentric exercise-induced skeletal muscle injury by down-regulating NF-κb mediated inflammation.

Author: LiouKuo-Tong, ShenYuh-Chiang, YenJiin-Cherng

Paper Details 
Original Abstract of the Article :
BACKGROUND AND PURPOSE: Caffeic acid phenethyl ester (CAPE), a phenolic compound isolated from propolis, displays a variety of biological activities. The aim is to examine the protective effect and mechanisms of CAPE on an eccentric exercise-induced muscle injury model. EXPERIMENTAL APPROACH: An in...See full text at original site
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引用元:
https://doi.org/10.1159/000348412

データ提供:米国国立医学図書館(NLM)

Caffeic Acid Phenethyl Ester: A Shield Against Muscle Damage

Dr. Camel here, ready to explore the potential of [caffeic acid phenethyl ester (CAPE)] in protecting against muscle damage. Eccentric exercise, a type of exercise that involves lengthening a muscle while contracting, can lead to muscle damage, much like the wear and tear on a camel's hooves during a long journey across the desert. This study investigates the protective effects of CAPE against eccentric exercise-induced muscle injury in rats. The researchers found that CAPE effectively reduced muscle damage, inflammation, and oxidative stress, potentially by inhibiting the activation of nuclear factor-κB (NF-κB), a key regulator of inflammatory responses. This research suggests that CAPE may have therapeutic potential for preventing or treating muscle injuries, offering a natural shield against the harsh conditions of muscle damage.

A Natural Shield Against Muscle Damage

This research highlights the potential of CAPE as a natural protector against muscle damage. Its ability to reduce inflammation and oxidative stress associated with muscle injury is a promising finding. It's like discovering a resilient desert plant that can withstand harsh conditions and offer protection against the elements, providing a natural defense against muscle damage.

Protecting Our Muscles from the Sandstorm

This research sheds light on the potential of natural compounds like CAPE in protecting our muscles from damage. It's a reminder that even in the face of challenging conditions, we can find natural solutions that can help us navigate the desert landscape of muscle injuries.

Dr. Camel's Conclusion

This study unveils the potential of CAPE as a natural protector against muscle damage. Its ability to reduce inflammation and oxidative stress offers hope for future treatments and prevention strategies. It's a reminder that even in the vast desert of medical research, we can find valuable resources, just like a thirsty camel seeking a hidden oasis.

Date :
  1. Date Completed 2013-12-17
  2. Date Revised 2013-05-21
Further Info :

Pubmed ID

23571777

DOI: Digital Object Identifier

10.1159/000348412

Related Literature

SNS
PICO Info
in preparation
Languages

English

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