Swift onset of central nervous system depression and asystole followingan overdose of Guaifenesin.

Author: CrifasiJoseph A, JohnsonTom, LongChristopher, MitchellErik K, OkicMerisa

Paper Details 
Original Abstract of the Article :
Guaifenesin is an over-the-counter expectorant used for chest congestion and is available both in single-ingredient formulations and in combination with antihistamines, cough suppressants and decongestants. The documented side-effects of guaifenesin are generally mild. We present the case of a 23-ye...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1093/jat/bkt030

データ提供:米国国立医学図書館(NLM)

Guaifenesin Overdose: A Silent Killer?

Guaifenesin is a common over-the-counter expectorant used for chest congestion. While generally safe, this study reveals a fatal case of guaifenesin overdose, highlighting the importance of recognizing its potential toxicity.

A Case of Unexpected Death

A 23-year-old female committed suicide by ingesting guaifenesin, along with small amounts of other medications. The initial toxicology report only detected ethanol at insufficient levels to cause death. However, further analysis revealed high levels of guaifenesin in her blood, urine, and organs, indicating that this medication was the likely cause of death. This case demonstrates the crucial role of thorough toxicological analysis in identifying the true cause of death, especially in cases of suspected overdose.

The Importance of Thorough Analysis

Guaifenesin might not be detected by all toxicology tests, making it crucial to consider it as a possible cause of death, especially in cases of overdose or suspected poisoning. This case serves as a reminder for healthcare professionals to be vigilant and ensure comprehensive toxicology analyses are conducted to identify potential drug-related fatalities.

Dr.Camel's Conclusion

This case study reminds us that even seemingly innocuous medications can be dangerous when misused. It emphasizes the importance of careful drug use and the need for comprehensive toxicology analysis in cases of overdose or suspected poisoning. As a researcher, it's like sifting through sand in the desert to uncover hidden clues, leading to a deeper understanding of the true cause of death.

Date :
  1. Date Completed 2013-12-03
  2. Date Revised 2013-05-14
Further Info :

Pubmed ID

23580607

DOI: Digital Object Identifier

10.1093/jat/bkt030

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.