Immunogenicity, safety and tolerability of 3 lots of 13-valent pneumococcal conjugate vaccine given with routine pediatric vaccinations in the United States.

Author: EminiEmilio A, FrenckRobert W, GirgentiDouglas, GruberWilliam C, LoveJack, PattersonScott, PaytonTerry, RazmpourAhmad, ScottDaniel A, SidhuMohinder S

Paper Details 
Original Abstract of the Article :
The 7-valent pneumococcal conjugate vaccine (PCV7; serotypes 4, 6B, 9V, 14, 18C, 19F and 23F) has decreased invasive pneumococcal disease incidence. This study was performed to support licensure of a 13-valent pneumococcal conjugate vaccine (PCV13), which expands serotype coverage to include serotyp...See full text at original site
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引用元:
https://doi.org/10.1097/INF.0b013e3182906499

データ提供:米国国立医学図書館(NLM)

Expanding the Horizons of Pneumococcal Vaccine Protection

In the vast expanse of pediatric healthcare, [pneumococcal conjugate vaccines (PCVs)] are like protective shields against potentially dangerous infections. This study embarks on a journey to investigate the safety and effectiveness of a new generation of PCV, known as [PCV13], which broadens its coverage to include additional strains of the pneumococcal bacteria. The researchers meticulously evaluated the immunogenicity, safety, and consistency of PCV13, seeking to ensure its suitability for use in young children.

A New Frontier in Pneumococcal Vaccination

The study's findings suggest that PCV13 effectively protects against a wider range of pneumococcal strains. This discovery is akin to discovering a hidden oasis in a desert, providing much-needed protection for children. The researchers also demonstrated that PCV13 exhibits a favorable safety profile, further solidifying its potential as a valuable addition to the pediatric vaccine arsenal.

A Shield for Young Explorers

The development of PCV13 offers a significant advancement in the fight against pneumococcal infections in children. It's like a new layer of defense against the dangers of this prevalent bacteria, providing an extra layer of protection for young explorers venturing into the world. This research emphasizes the importance of continuously exploring new and improved vaccines to safeguard the health of our youngest generations.

Dr.Camel's Conclusion

This study, much like a caravan traversing a desert, brings us closer to a future where pneumococcal infections are less of a threat to children. PCV13 holds the potential to further strengthen our defenses against these infections, ensuring a safer and healthier journey for the next generation.

Date :
  1. Date Completed 2014-05-09
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

23584582

DOI: Digital Object Identifier

10.1097/INF.0b013e3182906499

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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