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Incidence of rash after amoxicillin treatment in children with infectious mononucleosis.

Author: Ben TovAmir, Chovel-SellaAluma, LahavEinat, MorOrna, ParetGideon, ReifShimon, RudichHagit

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Overview

The incidence of ampicillin-associated rash in patients with Epstein-Barr virus acute infectious mononucleosis (AIM), initially reported as 80-100%, was investigated in a recent study. The aim was to determine the current incidence of rash associated with antibiotic treatment in children with AIM.
Paper Details　
Original Abstract of the Article :
"Ampicillin rash," a phenomenon unique to patients with Epstein-Barr virus acute infectious mononucleosis (AIM) treated with ampicillin, was first reported in the 1960s. The incidence was estimated as being between 80% and 100%, and the figures have not been reviewed since those first accounts. We s...See full text at original site
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引用元：
https://doi.org/10.1542/peds.2012-1575

データ提供：米国国立医学図書館（NLM）

Ampicillin Rash in Infectious Mononucleosis: A Reappraisal of Incidence

Infectious mononucleosis, caused by the Epstein-Barr virus, often presents unique challenges in treatment. This research revisits the phenomenon of 'ampicillin rash,' a well-known complication associated with ampicillin treatment in patients with infectious mononucleosis. The authors sought to determine the current incidence of this rash among children with this condition.

Ampicillin Rash Remains a Significant Risk: A Reappraisal of Incidence

The study findings indicate that ampicillin rash continues to be a significant risk in patients with infectious mononucleosis. The authors conclude that clinicians should be aware of this potential complication and consider alternative antibiotics when treating children with this condition.

Navigating Antibiotic Treatment for Infectious Mononucleosis: A Guide for Clinicians

This research underscores the importance of considering the specific characteristics of each patient and the potential complications associated with different treatment options. The findings provide valuable information for clinicians seeking to optimize antibiotic therapy for infectious mononucleosis.

Dr. Camel's Conclusion

The world of medicine is filled with surprises, and ampicillin rash is a reminder that even well-established treatments can have unexpected consequences. This research provides valuable insights into the current incidence of this complication, helping clinicians make informed decisions about antibiotic therapy for infectious mononucleosis.

Date :
  1. Date Completed 2013-07-17
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

23589810

DOI: Digital Object Identifier

10.1542/peds.2012-1575

Related Literature

Article Analysis
・Effective treatment of infectious mononucleosis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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