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Efficacy of cevimeline vs. pilocarpine in the secretion of saliva: a pilot study.

Author: BrimhallJae, JhaveriMalhar A, YepesJuan F

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Both cevimeline and pilocarpine increased the secretion of saliva in patients with xerostomia, with a slightly higher increment in saliva with pilocarpine.
Paper Details　
Original Abstract of the Article :
OBJECTIVES: To determine the efficacy and compare the side-effects of cevimeline and pilocarpine in the secretion of saliva in patients with xerostomia. METHODS: A randomized, cross-over, double blind study was designed. Fifteen patients with diagnosis of xerostomia were assigned to take either 5 m...See full text at original site
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引用元：
https://doi.org/10.1111/scd.12010

データ提供：米国国立医学図書館（NLM）

Cevimeline and Pilocarpine: A Comparative Oasis in the Desert of Xerostomia

Xerostomia, or dry mouth, is a common condition that can significantly impact quality of life. This study explores the efficacy and side-effects of two medications, cevimeline and pilocarpine, in stimulating saliva production. The authors conducted a randomized, crossover, double-blind trial to compare the effectiveness of these drugs in treating xerostomia.

A Promising Oasis in the Desert of Dry Mouth

This research provides encouraging findings for individuals suffering from xerostomia. Both cevimeline and pilocarpine demonstrated effectiveness in increasing saliva production, offering potential relief for this distressing condition. While the study found no significant difference between the two medications, it suggests that both could be valuable tools in managing dry mouth.

Navigating the Desert of Treatment Options

The availability of effective treatment options for xerostomia is a welcome oasis in the desert of dry mouth. This study provides valuable insights into the potential benefits of cevimeline and pilocarpine, offering patients and their healthcare providers a broader range of treatment options. Further research is needed to determine the optimal use of these medications and identify potential long-term effects.

Dr.Camel's Conclusion

This study provides a much-needed oasis in the desert of dry mouth, offering hope for individuals struggling with this uncomfortable condition. The findings suggest that cevimeline and pilocarpine can be effective in increasing saliva production. While further research is needed to refine the use of these medications, this study provides a positive step toward improving the lives of patients with xerostomia.

Date :
  1. Date Completed 2014-03-26
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

23600983

DOI: Digital Object Identifier

10.1111/scd.12010

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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