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Overdose of drugs for attention-deficit hyperactivity disorder: clinical presentation, mechanisms of toxicity, and management.

Author: AleguasAlfred, HaysHannah L, SpillerHenry A

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This review focuses on the mechanisms of toxicity, clinical effects, and management of overdose with ADHD medications. Amphetamine, dextroamphetamine, and methylphenidate overdose can lead to neurological and cardiovascular complications. Modafinil overdose is generally mild, while atomoxetine overdose is usually associated with drowsiness, agitation, and gastrointestinal upset. Clonidine overdose primarily affects neurological and cardiovascular systems, while guanfacine overdose can have mixed effects.
Paper Details　
Original Abstract of the Article :
The prevalence of attention-deficit hyperactivity disorder (ADHD) in the USA is estimated at approximately 4-9% in children and 4% in adults. It is estimated that prescriptions for ADHD medications are written for more than 2.7 million children per year. In 2010, US poison centers reported 17,000 hu...See full text at original site
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引用元：
https://doi.org/10.1007/s40263-013-0084-8

データ提供：米国国立医学図書館（NLM）

Attention-Deficit Hyperactivity Disorder (ADHD) Medication Overdose: Navigating a Storm

Attention-Deficit Hyperactivity Disorder (ADHD) is a common condition, and the medications used to manage its symptoms can present risks if overdosed. This study examines the mechanisms of toxicity, clinical presentation, and management of overdose with ADHD medications, including stimulants (amphetamine, methylphenidate, modafinil) and non-stimulants (atomoxetine, guanfacine, clonidine). The researchers provide a comprehensive overview of the potential complications and appropriate management strategies for these overdoses.

A Guide Through the Labyrinth of ADHD Overdose

The study's findings highlight the importance of understanding the specific mechanisms of toxicity for each ADHD medication. The researchers detail the clinical effects, such as neurological and cardiovascular complications, and provide guidance on managing these overdoses, including supportive care, benzodiazepines, and antipsychotics. This information is crucial for healthcare professionals to effectively respond to overdose situations.

Staying Safe in the Realm of ADHD Medications

This study underscores the importance of patient education and safe medication practices. Individuals with ADHD should understand the risks associated with medication overdose, store their medications securely, and be aware of the potential symptoms and appropriate management strategies. Close collaboration between patients, caregivers, and healthcare providers is essential to minimize the risk of overdose and ensure safe and effective treatment.

Dr.Camel's Conclusion

Navigating the world of ADHD medications requires a delicate balance of managing symptoms while minimizing risks. This study provides a comprehensive overview of overdose management, emphasizing the importance of understanding the specific mechanisms of toxicity for each medication. By promoting patient education and safe medication practices, we can better ensure the well-being of individuals with ADHD.

Date :
  1. Date Completed 2014-02-03
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

23757186

DOI: Digital Object Identifier

10.1007/s40263-013-0084-8

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Languages

English

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