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A literature review of cost-effectiveness analyses of prostate-specific antigen test in prostate cancer screening.

Author: BorregoMatthew E, GargVishvas, GuNing Yan, RaischDennis W

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Prostate cancer is a common cancer in men. The US Preventive Services Task Force recommends against PSA-based screening, while other organizations continue to recommend it. This study reviewed the cost-effectiveness of PSA-based screening, finding that it is cost-effective for younger men and those with higher PSA levels.
Paper Details　
Original Abstract of the Article :
Prostate cancer is the most common non-skin cancer in American men, and prostate-specific antigen (PSA) testing is its common screening procedure. In May 2012, the US Preventive Services Task Force recommended against PSA-based screening. These recommendations contradict the current recommendations ...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1586/erp.13.26

データ提供：米国国立医学図書館（NLM）

PSA Screening: A Cost-Effective Tool for Prostate Cancer Detection

The desert of prostate cancer research is vast and complex, with numerous studies exploring the best strategies for early detection and management. This research delves into the cost-effectiveness of prostate-specific antigen (PSA) testing for prostate cancer screening. The authors conducted a systematic review of published literature reporting the cost-effectiveness of PSA-based screening, analyzing studies from both the US and non-US jurisdictions. Their findings suggest that PSA-based screening is generally cost-effective in younger men (≤60 years of age) and at higher PSA levels (≥3 ng/ml).

Balancing Costs and Benefits: PSA Screening

The research provides evidence to support the cost-effectiveness of PSA-based screening in certain patient populations. The authors highlight the importance of considering age and PSA levels when evaluating the potential benefits and costs of PSA screening. They also underscore the need for further cost-effectiveness analyses that reflect the latest clinical practice and perspectives regarding the potential adverse outcomes of potentially unnecessary treatment.

Navigating the Sands of Prostate Cancer Screening: A Balanced Approach

The research highlights the importance of a balanced approach to prostate cancer screening. While PSA testing can be a valuable tool for early detection, it's crucial to weigh the potential benefits against the risks and costs. This study underscores the need for ongoing research to refine our understanding of the cost-effectiveness of PSA screening and guide clinical practice.

Dr. Camel's Conclusion

This systematic review provides a comprehensive analysis of the cost-effectiveness of PSA-based screening for prostate cancer. The authors have carefully reviewed the available evidence and identified key factors to consider when evaluating the potential benefits and costs of this screening strategy. Their findings offer valuable guidance for clinicians and policymakers in making informed decisions about prostate cancer screening.

Date :
  1. Date Completed 2014-02-03
  2. Date Revised 2018-12-03
Further Info :

Pubmed ID

23763530

DOI: Digital Object Identifier

10.1586/erp.13.26

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・Effective treatment of prostate cancer screening
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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