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In vitro cytokine expression by peripheral mononuclear cells in herbal drug-induced skin eruption.
Author: NorisugiOsamu, ShimizuKyoko, ShimizuTadamichi, YoshihisaYoko
Original Abstract of the Article :
Herbal medicine is widely used worldwide and is associated with side-effects such as skin eruptions. Herbal drugs are often produced by combining multiple crude drugs, mostly of plant origin. Determining which medi-cinal plants are associated with the herbal drugs that induce skin eruptions can ther...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.2340/00015555-1631
データ提供:米国国立医学図書館(NLM)
Unraveling the Complexities of Herbal Drug-Induced Skin Eruptions
Herbal medicine is a popular and often effective alternative treatment approach. However, it can sometimes cause adverse reactions, including skin eruptions. This research explores the complex mechanisms underlying herbal drug-induced skin eruptions, focusing on the role of cytokines in the immune response. The study investigated the expression of various cytokines in peripheral mononuclear cells (PBMCs) from patients experiencing skin eruptions following exposure to specific herbal drugs.
Cytokines: Key Players in Herbal Drug-Induced Skin Eruptions
The study found that specific herbal drugs, such as keishi-bukuryo-gan and senna, stimulated the production of certain cytokines, including IL-4 and IL-5, in PBMCs. These findings suggest that cytokines play a significant role in the immune response associated with herbal drug-induced skin eruptions.
Understanding the Immune Mechanisms of Herbal Drug Toxicity
This research contributes to our understanding of the immune mechanisms involved in herbal drug-induced skin eruptions. The findings highlight the importance of cytokines in mediating these adverse reactions and provide valuable insights for developing safer and more effective herbal therapies.
Dr.Camel's Conclusion
Imagine a desert oasis filled with a diverse array of plants, some beneficial and others potentially harmful. This research explores the intricate relationship between herbal medicine and the human immune system, shedding light on the mechanisms that can lead to skin eruptions. Understanding these complex interactions is essential for promoting safe and effective use of herbal therapies.
Date :
- Date Completed 2014-09-15
- Date Revised 2021-12-03
Further Info :
Related Literature
English
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