Gluten ataxia of sporadic and hereditary cerebellar ataxia in patients from mainland China.

Author: GuanWen-Juan, JiangHong, LiuXin-Jian, LiuYu-Tao, ShenLu, TangBei-Sha, WangJun-Ling, XiaKun, ZhouYing

Paper Details 
Original Abstract of the Article :
BACKGROUND: Gluten sensitivity (GS) is a spectrum of disorders with diverse manifestations. Recent evidence suggests that ataxia may be the only manifestation of GS and that it may be one of the causes of sporadic ataxia. AIM: To investigate the prevalence of gluten ataxia among patients with ataxi...See full text at original site
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引用元:
https://doi.org/10.4103/0028-3886.115056

データ提供:米国国立医学図書館(NLM)

Gluten Ataxia: A Hidden Oasis in the Desert of Neurological Disorders

The human body is a complex and delicate ecosystem, and sometimes, even seemingly harmless substances can trigger unexpected reactions. This research investigates the potential role of [gluten] in the development of [ataxia], a neurological disorder characterized by a loss of coordination and balance. The authors set out to determine the prevalence of gluten ataxia among patients with ataxia in China, exploring the potential link between dietary sensitivities and neurological conditions.

Unveiling the Mystery: Gluten's Potential Role in Ataxia

The study found that serum levels of anti-gliadin, anti-transglutaminase 2 (TG2), and anti-transglutaminase 6 (TG6) antibodies were elevated in ataxia patients, suggesting a potential link between gluten sensitivity and the development of ataxia. The results are like discovering a hidden oasis in the vast and complex desert of neurological disorders, revealing a possible connection between diet and neurological health. The study also found that TG6-IgA serum levels were significantly higher in sporadic ataxia patients compared to healthy controls, further strengthening the link between gluten sensitivity and ataxia.

Navigating the Dietary Desert: The Importance of Gluten Awareness

This research highlights the importance of considering gluten sensitivity as a possible contributing factor to ataxia. The study's findings are like a compass guiding us through the dietary desert, emphasizing the need for a careful evaluation of dietary factors in the diagnosis and management of ataxia. The authors suggest that measuring serum anti-TG6 antibodies, along with anti-TG2 and anti-gliadin antibodies, could be useful in diagnosing gluten ataxia.

Dr.Camel's Conclusion

This research sheds light on the potential role of gluten sensitivity in the development of ataxia, offering a new perspective on the connection between diet and neurological health. The study's findings suggest that further investigation into the role of gluten in ataxia is warranted, potentially leading to a better understanding of this complex neurological disorder and the development of more targeted treatment approaches.

Date :
  1. Date Completed 2013-09-11
  2. Date Revised 2021-04-06
Further Info :

Pubmed ID

23860139

DOI: Digital Object Identifier

10.4103/0028-3886.115056

Related Literature

SNS
PICO Info
in preparation
Languages

English

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