Neurological and psychiatric adverse events with prucalopride: case report and possible mechanisms.

Author: AntoniazziS, CarnovaleC, ClementiE, NisicA, PellegrinoP, PerroneV, PozziM, RadiceS

Paper Details 
Original Abstract of the Article :
Chronic constipation is very frequent in the general population. Although usually considered banal, this disorder has considerable personal, social and healthcare impact. Several studies have shown that the psychological impact exceeds that caused by rheumatoid arthritis or haemodialysis. Recently, ...See full text at original site
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引用元:
https://doi.org/10.1111/jcpt.12087

データ提供:米国国立医学図書館(NLM)

Prucalopride and Neurological Side Effects: A Case Report

The field of gastroenterology is always seeking better ways to manage chronic constipation. This study delves into the potential neurological side effects of prucalopride, a medication commonly used to treat this condition. The authors present a case study of a 61-year-old woman who experienced adverse neurological and psychiatric effects after taking prucalopride. This is an important observation as prucalopride has been considered a safe and effective treatment for chronic constipation. This research raises concerns about the potential for neurological side effects and highlights the need for further investigation into the safety profile of prucalopride, especially in individuals with a predisposition to neurological issues.

Exploring the Potential Risks

The discovery of neurological side effects in this case study raises a crucial question: could prucalopride be affecting the brain in ways we haven't fully understood? While this is a single case report, it serves as a valuable reminder that even seemingly safe medications can have unexpected effects on the body. It's like a camel traversing a vast desert, finding an oasis but discovering hidden dangers lurking beneath its surface. This research encourages us to examine the potential risks and benefits of prucalopride with greater scrutiny.

Navigating Constipation: A Holistic Approach

Constipation can be a real desert of discomfort. It's essential to remember that every individual responds differently to medication. If you are experiencing chronic constipation, it's vital to consult with your physician to explore all treatment options. This might involve lifestyle changes, dietary adjustments, or perhaps alternative medications. A holistic approach to managing constipation will help us journey through this desert with greater comfort and clarity.

Dr. Camel's Conclusion

This case study serves as a valuable reminder that even seemingly safe medications can have unexpected effects. It's important to approach all medications with caution and consult with your healthcare provider to discuss any potential risks and benefits. While prucalopride has proven to be effective for many individuals, the potential for neurological side effects should not be overlooked. Remember, like the sands of the desert, every individual's journey is unique, and what works for one might not work for another.

Date :
  1. Date Completed 2014-10-21
  2. Date Revised 2014-03-03
Further Info :

Pubmed ID

23889005

DOI: Digital Object Identifier

10.1111/jcpt.12087

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SNS
PICO Info
in preparation
Languages

English

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