A family cluster of giardiasis with variable treatment responses: refractory giardiasis in a family after a trip to India.

Author: AldasoroE, ClavelA, GascónJ, GoñiP, LóbezS, MuñozJ, OliveiraI, Requena-MéndezA, VallsM-E

Paper Details 
Original Abstract of the Article :
Persistence of giardiasis after some of the recommended drugs is occurring with increasing frequency. We describe the follow-up of four members of a family with giardiasis through microscopic observation, immunochromatography and PCRs of tpi and β-giardin genes. Three patients did not respond to tin...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/23926944

データ提供:米国国立医学図書館(NLM)

Giardiasis: A Persistent Desert of Infection

Giardiasis, a parasitic infection of the small intestine, can be a persistent and troublesome condition. This case report describes a family cluster of giardiasis with variable treatment responses, highlighting the challenges of managing this infection. The researchers followed four family members with giardiasis, examining their treatment responses to different medications and evaluating the effectiveness of PCR for detecting Giardia infection.

Navigating the Giardiasis Desert: Variable Treatment Responses

The study revealed that three family members did not respond to tinidazole but were successfully treated with quinacrine. However, PCR remained positive for some time even after stool samples became negative, suggesting that PCR may not be a reliable indicator of complete eradication of Giardia infection.

A Need for Further Exploration: Understanding Giardia Infection

This case report highlights the complexities of giardiasis and emphasizes the need for further research to improve diagnosis, treatment, and prevention strategies for this persistent parasitic infection.

Dr. Camel's Conclusion

This case report illustrates the challenges of managing giardiasis, particularly in the context of variable treatment responses. It emphasizes the need for careful diagnosis, appropriate treatment selection, and further research to develop more effective strategies for managing this persistent parasitic infection.

Date :
  1. Date Completed 2014-08-29
  2. Date Revised 2018-12-03
Further Info :

Pubmed ID

23926944

DOI: Digital Object Identifier

S1198-743X(14)60062-8

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.